Amphotericin-B (250 µg/mL) 20 mL

Amphotericin-B (250 µg/mL) 20 mL

Synonyms Fungizone

CAS Number: 1397-89-3 Molecular Formula: C47H73NO17 Molecular Weight: 924.08

EC Number: 215-742-2

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SKU 0916723-CF
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Description

Product Description

Amphotericin B is a polyene antifungal antibiotic from Streptomyces sp. It has a high affinity for sterols, primarily ergosterols, of fungal and bacterial cell membranes. It is an antibiotic solution effective against yeast and other fungi. Amphotericin B may be toxic to some insect cell types. Amphotericin B, is an antimycotic.

Application Notes

Amphotericin B is used as antifungal in cell culture media.

Key Applications

Cell culture applications | Antimicrobial Treatment

Specifications
SKU 0916723-CF
Alternate Names Fungizone
Application Notes Amphotericin B is used as antifungal in cell culture media.
Concentration 250 µg/mL
EC Number 215-742-2
Formulation Liquid | It is formulated with deoxycholate and prepared in water for increased solubility.
Applications Cell culture applications | Antimicrobial Treatment
Molecular Formula C<sub>47</sub>H<sub>73</sub>NO<sub>17</sub>
Molecular Weight 924.08
Physical Appearance Yellow Solution
Presentation It is formulated with deoxycholate and prepared in water for increased solubility. | Solution
Solubility Slightly soluble in water; DMF/1M HCL 3/1: 49.00 - 51.00 mg/mL; Amphotericin B is insoluble in water at pH 6 to 7, but soluble in water at pH 2 or 11. It is soluble in DMSO (30 – 40 mg/mL) and in dimethylformamide (2 – 4 mg/mL).
Sterility Sterile
Storage and Handling Store at -20°C.
Typical Working Concentration 0.25 – 2.5 μg/mL