17αHP Double Antibody RIA Kit
The 17αHP Double Antibody RIA Kit is intended for the measurement of 17α-hydroxyprogesterone in unextracted serum or plasma of adults and children. The steroid 17α-hydroxyprogesterone (17αHP) is produced by both the adrenal cortex and gonads. Even though 17αHP has relatively little progestational activity, it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). Because Cpd-S is produced by 21-hydroxylation of 17αHP, measurement of 17αHP is a useful indirect indicator of 21-hydroxylase activity. In congenital 21-hydroxylase deficiency, the most common variety of congenital adrenal hyperplasia (CAH), 17αHP is secreted in abundant excess. It is moderately elevated in the 11-b-hydroxylase deficiency as well. Measurement of 17αHP is therefore valuable in the initial diagnosis of CAH.
FDA cleared for In Vitro Diagnostic (IVD) use in the United States. CE Marked for IVD use outside the United States.
|Analyte / Target||17OHP (17 alpha hydroxyprogesterone)|
|Kit or Assay Type||Liquid Phase Radioimmunoassay|
|Pack Size||100 Tubes|
|Product Overview||The kit is ready to use and includes the following components: Antiserum, 7 standards, 125I-labeled tracer, Steroid Diluent, and Precipitant Solution. Kits are manufactured once per month and have an 8 week shelf life.|
|Recommended Replacement For||07271102 | 07271105 | 07271305 | 07271302 | 07M5525303|
|Regulatory Compliance||FDA Cleared (K840886)|
|Sample Volume||25 uL|
|Standards||0, 0.10, 0.25, 1.0, 2.5, 10.0, 25.0 ng/mL|
|Storage and Handling||Store at 2 - 8C|
|Usage Statement||FDA cleared for In Vitro Diagnostic (IVD) use in the United States. CE Marked for IVD use outside the United States.|