17α-Hydroxyprogesterone Double Antibody RIA Kit

17α-Hydroxyprogesterone Double Antibody RIA Kit

Packaging size: 100 Tubes

SKU 07171102
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Description

Product Description

The 17αOHP Double Antibody RIA Kit is intended for the measurement of 17α-hydroxyprogesterone in unextracted serum or plasma of adults and children. The steroid 17α-hydroxyprogesterone (17αOHP) is produced by both the adrenal cortex and gonads. Even though 17αOHP has relatively little progestational activity, it is of intense clinical interest because it is the immediate precursor to 11-desoxycortisol (Cpd-S). Because Cpd-S is produced by 21-hydroxylation of 17αOHP, measurement of 17αOHP is a useful indirect indicator of 21-hydroxylase activity. In congenital 21-hydroxylase deficiency, the most common variety of congenital adrenal hyperplasia (CAH), 17αOHP is secreted in abundant excess. It is moderately elevated in the 11-b-hydroxylase deficiency as well. Measurement of 17αOHP is therefore valuable in the initial diagnosis of CAH.

Usage Statement

FDA cleared for In Vitro Diagnostic (IVD) use in the United States. CE Marked for IVD use outside the United States.

Key Applications

Endocrinology

Specifications
SKU 07171102
Analyte / Target 17OHP (17 alpha hydroxyprogesterone)
Diagnostic Platforms RIA
Diagnostic Solutions Endocrinology
Disease Screened 17OHP
Evaluation Quantitative
Isotope 125I
Applications Endocrinology
Kit or Assay Type Liquid Phase Radioimmunoassay
Pack Size 100 Tubes
Product Overview The kit is ready to use and includes the following components: Antiserum, 7 standards, 125I-labeled tracer, Steroid Diluent, and Precipitant Solution. Kits are manufactured once per month and have an 8 week shelf life.
Recommended Replacement For 07271102 | 07271105 | 07271305 | 07271302 | 07M5525303
Regulatory Compliance FDA Cleared (K840886)
Sample Type Serum|Plasma
Sample Volume 25 uL
Species Reactivity human
Standards 0, 0.10, 0.25, 1.0, 2.5, 10.0, 25.0 ng/mL
Storage and Handling Store at 2 - 8C
Usage Statement FDA cleared for In Vitro Diagnostic (IVD) use in the United States. CE Marked for IVD use outside the United States.