Sodium Bicarbonate

Sodium Bicarbonate

Synonyms Sodium Hydrogen Carbonate; Baking Soda; Carbonic acid monosodium salt; Monosodium carbonate

CAS Number: 144-55-8 Molecular Formula: NaHCO3 Molecular Weight: 84.006 g/mol

Beilstein Registry Number: 4153970 EC Number: 205-633-8 MDL Number: MFCD00003528

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SKU 02195497-CF
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Description

Product Description

Sodium Bicarbonate

Application Notes

Sodium bicarbonate is broadly used as a physiological buffer in cell culture applications. The pKa for bicarbonate <-> carbonic acid reaction is 6.4 The pKa for bicarbonate <-> carbonate reaction is 10.3. Sodum bicarbonate has two pKas, 6.4 and 10.3. The compound can react with both acids and bases, therefore it can be used as a neutralizer. Sodium bicarbonate may be used to remove or wash acidic impurities from a crude liquid to yield a purer sample. Sodium bicarbonate reacts with the carboxyl groups to give a fast-forming and effervescent CO2 formation which has been used to test for the presence of carboxylic groups in proteins.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Biological Buffers||Buffers||Cell Biology||Cell Culture||Cell Signaling||Laboratory pH neutralizer that reacts with acids and bases

Specifications
SKU 02195497-CF
Application Notes Sodium bicarbonate is broadly used as a physiological buffer in cell culture applications. The pKa for bicarbonate <-> carbonic acid reaction is 6.4 The pKa for bicarbonate <-> carbonate reaction is 10.3. Sodum bicarbonate has two pKas, 6.4 and 10.3. The compound can react with both acids and bases, therefore it can be used as a neutralizer. Sodium bicarbonate may be used to remove or wash acidic impurities from a crude liquid to yield a purer sample. Sodium bicarbonate reacts with the carboxyl groups to give a fast-forming and effervescent CO2 formation which has been used to test for the presence of carboxylic groups in proteins.
Beilstein Registry Number 4153970
Density 2.159 (NTP, 1992)
EC Number 205-633-8
Format powder
Hazard Statements H303
Applications Biological Buffers||Buffers||Cell Biology||Cell Culture||Cell Signaling||Laboratory pH neutralizer that reacts with acids and bases
Melting Point Decomposes at 228° F (NTP, 1992)
Molecular Formula NaHCO3
Molecular Weight 84.006 g/mol
Pack Size No
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
pH Between 8,0 and 8,6 (1 % solution)
Physical Appearance White Powder
pKa (1) 6.37, (2) 10.25 (carbonic acid)(Lit.)
Product Families Description Sodium bicarbonate
Product Overview Sodium Bicarbonate
Purity ≥99.5%
Refractive Index 1.500(Lit.)
RTECS Number VZ0950000
Solubility 1 in 10 % at 77° F (NTP, 1992)
Storage and Handling Store at Room Temperature (15-30 °C).
TSCA Yes
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.