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Sodium Selenite

Sodium Selenite

Synonyms Selenious Acid, Disodium; Disodium selenite; Natriumselenit; Selenious acid, disodium salt

CAS Number: 10102-18-8 Molecular Formula: Na2SeO3 Molecular Weight: 172.948 g/mol

EC Number: 233-267-9 MDL Number: MFCD00003489

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SKU 02194741-CF
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Description

Product Description

Sodium Selenite

Application Notes

Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite is included in various medium supplements for use in cell culture. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Specifications
SKU 02194741-CF
Application Notes Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite is included in various medium supplements for use in cell culture. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.
Boiling Point Decomposes (NTP, 1992)
Density 3.1 (NTP, 1992)
EC Number 233-267-9
Format powder
Grade Cell Culture Reagent
Hazard Statements H300-H317-H331-H411; Contact with acids liberates toxic gas.
Melting Point 1310° F (decomposes) (NTP, 1992)
Molecular Formula Na2SeO3
Molecular Weight 172.948 g/mol
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator , Gloves, respirator cartridge , Respirator filter
Physical Appearance Pale Gray Powder
Product Families Description Sodium selenite
Product Overview Sodium Selenite
Purity ~98%
RTECS Number VS7350000
Safety Symbol GHS06, GHS09
Solubility greater than or equal to 100 mg/mL at 70.7° F (NTP, 1992)
Storage and Handling Store at Room Temperature (15-30 °C).
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Vapor Pressure less than 0.001 mm Hg at 68° F (NTP, 1992)