Epidermal Growth Factor 95%

Epidermal Growth Factor 95%

Synonyms EGF; Epidermal cell growth factor

CAS Number: 62229-50-9 Molecular Weight: 6100

EC Number: 263-468-7

Packaging size: 100 µg

SKU 0216003501
Price:
$273.45
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Description

Product Description

Epidermal growth factor or EGF is a growth factor isolated from mouse submaxillary glands that stimulates cell growth, proliferation, and differentiation by binding to its receptor EGFR. EGF is mitogenic for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa and SV40-3T3 cells.

Application Notes

EGF stimulates the proliferation and differentiation of a wide variety of cell types deriving both from ectoderm and mesoderm. In tissue culture, EGF can act to reduce or eliminate the requirement for serum and is often used in conjunction with other media additives and hormones, such as insulin, transferrin, and prostaglandin E1. Cellular metabolic effects of EGF include stimulation of ion fluxes, glucose transport, glycolysis, and synthesis of DNA, RNA and proteins.

Key Applications

Mammalian Cell Culture |Molecular Biology | Stimulates proliferation of cells

Specifications
SKU 0216003501
Application Notes EGF stimulates the proliferation and differentiation of a wide variety of cell types deriving both from ectoderm and mesoderm. In tissue culture, EGF can act to reduce or eliminate the requirement for serum and is often used in conjunction with other media additives and hormones, such as insulin, transferrin, and prostaglandin E1. Cellular metabolic effects of EGF include stimulation of ion fluxes, glucose transport, glycolysis, and synthesis of DNA, RNA and proteins.
EC Number 263-468-7
Formulation Details Lyophilized
Grade Tissue Culture Grade
Applications Mammalian Cell Culture |Molecular Biology | Stimulates proliferation of cells
Molecular Weight 6100
Pack Size 100 µg
Physical Appearance White Solid
Preparation Method The sample should be dissolved in sterile water or a sterile albumin supplemented buffer. Solutions of pure EGF should be aliquoted and lyophilized, while solutions containing albumin may be stored at -20 °C.
Presentation Lyophilized from a solution of 0.01M sodium acetate | Solid
Purity ≥95%
Source Mouse Submaxillary Gland
Storage and Handling Store at +4°C. Store dessicated.