Dino

Poly-L-Lysine Hydrobromide

Poly-L-Lysine Hydrobromide

CAS Number: 25988-63-0 Molecular Weight: 402.54 g/mol

MDL Number: MFCD00237230

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SKU 02152689-CF
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Description

Product Description

Poly-L-Lysine Hydrobromide

Application Notes

Poly-L-Lysine is typically used as a coating substrate for culture dishes, slides, etc. It can be used in conjugation to methotrexate for increased drug transport. For Microencapsulation of islets. It is also use in simple reproducible procedure for chromosomal preparations from a variety of tissues. For immobilation of living cells in biocompatible semipermeable microcapsules. In the preparation of polycationic beads. Conjugation to albumin and horseradish peroxidase to enhance cellular uptake.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Coating substrate for culture dishes; slides||Cell adhesion

Specifications
SKU 02152689-CF
Analysis Note All molecular weights are calculated from the viscosity of the parent compound Poly-epsilon-Z-L-Lysine.
Application Notes Poly-L-Lysine is typically used as a coating substrate for culture dishes, slides, etc. It can be used in conjugation to methotrexate for increased drug transport. For Microencapsulation of islets. It is also use in simple reproducible procedure for chromosomal preparations from a variety of tissues. For immobilation of living cells in biocompatible semipermeable microcapsules. In the preparation of polycationic beads. Conjugation to albumin and horseradish peroxidase to enhance cellular uptake.
Biochemical Physiological Actions Poly-L-Lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has been proven useful as a vector for gene therapy. Poly-L-lysine is a nonspecific attachment factor for cells useful in promoting cell adhesion to solid substrates by enhancing electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When it is absorbed to the cell culture surface, poly-L-lysine functions to increase the number of positively charged sites available for cell binding. With cells that can digest poly-L-lysine, poly-D-lysine should be used as the attachment factor.
Format powder
Applications Coating substrate for culture dishes; slides||Cell adhesion
Molecular Weight 402.54 g/mol
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Physical Appearance Cream Powder
Product Families Description Poly-L-lysine hydrobromide
Product Overview Poly-L-Lysine Hydrobromide
Storage and Handling Store at -0 °C.
Typical Working Concentration Stock Solution for coating of culture dishes/slides: Dissolve 10 mg poly-L-lysine in 1 mL sterile, deionized water. This creates a 1% solution. Effective coating solution concentration for culture dishes will be 0.3 to 0.5% and for histology slides at 0.1%.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.