Ethylenediamine Tetraacetic Acid

Ethylenediamine Tetraacetic Acid

Synonyms EDTA; (Ethylenedinitrilo)tetraacetic acid; Edathamil; Ethylenedinitrilotetraacetic acid

CAS Number: 6381-92-6 Molecular Formula: C10H16N2O8 Molecular Weight: 372.238 g/mol

Beilstein Registry Number: 1716295 EC Number: 200-449-4 MDL Number: MFCD00003541

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SKU 02152521-CF
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Description

Product Description

Ethylenediamine Tetraacetic Acid

Application Notes

Ethylenediamine tetraacetic acid (EDTA) is a calcium chelator used to eliminate inhibition of enzyme catalyzed reactions due to traces of heavy metals. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. EDTA prevents platelet aggregation and is therefore the preferred anticoagulant for platelet counts. It is an inhibitor of metalloproteases and metal-activated proteases. It acts as a chelator of the zinc ion in the active site of metalloproteases, but EDTA can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. EDTA interferes with biological processes which are metal-dependent. It is a buffer component.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Chelating agent||Buffer Component

Specifications
SKU 02152521-CF
Alternate Names EDTA; (Ethylenedinitrilo)tetraacetic acid; Edathamil; Ethylenedinitrilotetraacetic acid
Application Notes Ethylenediamine tetraacetic acid (EDTA) is a calcium chelator used to eliminate inhibition of enzyme catalyzed reactions due to traces of heavy metals. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. EDTA prevents platelet aggregation and is therefore the preferred anticoagulant for platelet counts. It is an inhibitor of metalloproteases and metal-activated proteases. It acts as a chelator of the zinc ion in the active site of metalloproteases, but EDTA can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. EDTA interferes with biological processes which are metal-dependent. It is a buffer component.
Beilstein Registry Number 1716295
EC Number 200-449-4
Flash Point Flash point is> 100 deg C,
Format powder
Grade ACS Reagent Grade
Hazard Statements H319
Heavy Metals Heavy Metal (as Pb): <0.001%, Iron (Fe): <0.005%
Applications Chelating agent||Buffer Component
MDL # MFCD00003541
Molecular Formula C10H16N2O8
Molecular Weight 372.238 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Gloves
Physical Appearance White Powder
pKa 2.0, 2.7, 6.2, 10.3 (Lit.)
Product Families Description Ethylenediaminetetraacetic acid
Product Overview Ethylenediamine Tetraacetic Acid
Purity ≥99.4%
Residue on Ignition <0.2%
RTECS Number AH4025000
Safety Symbol GHS07
Solubility In <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/water">water</a>, 1.0X10+6 mg/L (miscible) at 25 deg C (est)
Storage and Handling Store at Room Temperature(15-30 °C).
Typical Working Concentration EDTA is an inhibitor of metalloproteases and metal-activated proteases at an effective concentration of 1-10 µM.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
Vapor Pressure 7.57X10-17 mm Hg at 25 deg C (est)