Dino

Spermine Un3259-Iii (8)

Spermine Un3259-Iii (8)

Synonyms Diaminopropyltetramethylenediamine; Gerontine; Musculamine; Neuridine; N,N-bis(aminopropyl)-1,4-butanediamine; 4,9-Diaza-1,12-dodecanediamine

CAS Number: 71-44-3 Molecular Formula: C10H26N4 Molecular Weight: 202.3

Beilstein Registry Number: 1750791 EC Number: 200-754-2 MDL Number: MFCD00008215

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SKU 02152070-CF
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Description

Product Description

Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. Formed from spermidine through the addition of aminopropyl group to spermidine by spermine synthase. It is found as a polycation at physiological pH.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

DNA precipitation | Chromosome isolation | Crystallization of DNA

Specifications
SKU 02152070-CF
Beilstein Registry Number 1750791
Biochemical Physiological Actions Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
Boiling Point 141-142°C at 0.5 mm Hg;
EC Number 200-754-2
Flash Point 110 °C / 230 °F (lit.)
Hazard Statements H314
Applications DNA precipitation | Chromosome isolation | Crystallization of DNA
Melting Point 28-30°C (Lit.)
Molecular Formula C10H26N4
Molecular Weight 202.3
Pack Size No
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator ,Gloves, respirator cartridge, respirator filter
pH 11-14 (0.5% aq soln)
Physical Appearance Colorless Solid
Purity ≥97%
RTECS Number EJ7175000
Safety Symbol GHS05
Solubility Soluble in water (1% w/v), lower alcohol, chloroform; practically insoluble in ether, benzene, petroleum ether.
Storage and Handling +4°C; desiccate; store under nitrogen
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.