N-Propyl Gallate

N-Propyl Gallate

Synonyms Gallic Acid; Propyl Ester; Progallin P; n-Propyl Ester of 3,4,5-Trihydroxybenzoic Acid; Propyl gallate; n-Propyl-3,4,5-Trihydroxybenzoate; 3,4,5-Trihydroxybenzene-1-propylcarboxylate; 3.4.5-Tihydroxybenzoic acid n-propl ester

CAS Number: 121-79-9 Molecular Formula: C10H12O5 Molecular Weight: 212.201 g/mol

Beilstein Registry Number: 1877976 EC Number: 204-498-2 MDL Number: MFCD00002196

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SKU 02102747-CF
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Description

Product Description

N-Propyl Gallate

Application Notes

n-Propyl gallate is used as an anti-fade reagent in fluorescence microscopy to reduce photobleaching of fluorescent probes such as rhodamine and fluorescein.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Antioxidant

Specifications
SKU 02102747-CF
Alternate Names Gallic Acid; Propyl Ester; Progallin P; n-Propyl Ester of 3,4,5-Trihydroxybenzoic Acid; Propyl gallate; n-Propyl-3,4,5-Trihydroxybenzoate; 3,4,5-Trihydroxybenzene-1-propylcarboxylate; 3.4.5-Tihydroxybenzoic acid n-propl ester
Application Notes n-Propyl gallate is used as an anti-fade reagent in fluorescence microscopy to reduce photobleaching of fluorescent probes such as rhodamine and fluorescein.
Beilstein Registry Number 1877976
Biochemical Physiological Actions An antioxidant that exhibits antimicrobial activity. Propyl gallate has been reported to be an effective antioxidant-based hepatoprotector, both in vitro and in vivo. It has also been shown to prevent neuronal apoptosis and block the death of neurons exposed to FeSO4/GA as well as partially protect endothelial cells against TNF-induced apoptosis. However, propyl gallate induced single strand breaks in DNA at concentrations higher than 0.25 μM when it was combined with copper concentrations at 5 μM and above. Another report, however, found that incubation of isolated rat hepatocytes with propyl gallate at concentrations of >1 mM induced cell killing, whereas, a lower concentration of propyl gallate > 0.5 mM resulted in a ladder formation of soluble low-molecular weight DNA fragments, characteristic of apoptosis.
Boiling Point Decomposes (NTP, 1992)
Density 1.21 (NTP, 1992)
EC Number 204-498-2
Extinction Coefficient EmM = 10.2 (272 nm, 1 M HCl) (Lit.)
Flash Point 368° F (NTP, 1992)
Format powder
Hazard Statements H302-H317
Applications Antioxidant
MDL # MFCD00002196
Melting Point 302° F (NTP, 1992)
Molecular Formula C10H12O5
Molecular Weight 212.201 g/mol
Personal Protective Equipment Dust mask , Eyeshields, Faceshields, Gloves
pH pH = 6.3 (0.05% aqueous solution); pH = 5.9 (0.1% aqueous solution); pH = 5.7 (0.2% aqueous solution)
Physical Appearance Off-white Powder
pKa 8.11 (Lit.)
Product Families Description Propyl gallate
Product Overview N-Propyl Gallate
RTECS Number LW8400000
Safety Symbol GHS07
Solubility less than 1 mg/mL at 68° F (NTP, 1992)
Storage and Handling Store at Room Temperature (15-30 °C).
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Vapor Density 7.3 (NTP, 1992) (Relative to Air)
Vapor Pressure 2.6X10-7 mm Hg at 25 deg C (est)