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N-Propyl gallate

N-Propyl gallate

Synonyms Gallic Acid; Propyl Ester; Progallin P; n-Propyl Ester of 3,4,5-Trihydroxybenzoic Acid; Propyl gallate; n-Propyl-3,4,5-Trihydroxybenzoate; 3,4,5-Trihydroxybenzene-1-propylcarboxylate; 3.4.5-Tihydroxybenzoic acid n-propl ester

CAS Number: 121-79-9 Molecular Formula: C10H12O5 Molecular Weight: 212.201 g/mol

Beilstein Registry Number: 1877976 EC Number: 204-498-2 MDL Number: MFCD00002196

SKU 02102747-CF
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Description

Product Description

N-Propyl Gallate

Application Notes

n-Propyl gallate is used as an anti-fade reagent in fluorescence microscopy to reduce photobleaching of fluorescent probes such as rhodamine and fluorescein.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antioxidant

Specifications
SKU 02102747-CF
Alternate Names Gallic Acid; Propyl Ester; Progallin P; n-Propyl Ester of 3,4,5-Trihydroxybenzoic Acid; Propyl gallate; n-Propyl-3,4,5-Trihydroxybenzoate; 3,4,5-Trihydroxybenzene-1-propylcarboxylate; 3.4.5-Tihydroxybenzoic acid n-propl ester
Application Notes n-Propyl gallate is used as an anti-fade reagent in fluorescence microscopy to reduce photobleaching of fluorescent probes such as rhodamine and fluorescein.
Base Catalog Number 102747
Beilstein Registry Number 1877976
Biochemical Physiological Actions An antioxidant that exhibits antimicrobial activity. Propyl gallate has been reported to be an effective antioxidant-based hepatoprotector, both in vitro and in vivo. It has also been shown to prevent neuronal apoptosis and block the death of neurons exposed to FeSO4/GA as well as partially protect endothelial cells against TNF-induced apoptosis. However, propyl gallate induced single strand breaks in DNA at concentrations higher than 0.25 μM when it was combined with copper concentrations at 5 μM and above. Another report, however, found that incubation of isolated rat hepatocytes with propyl gallate at concentrations of >1 mM induced cell killing, whereas, a lower concentration of propyl gallate > 0.5 mM resulted in a ladder formation of soluble low-molecular weight DNA fragments, characteristic of apoptosis.
Boiling Point Decomposes (NTP, 1992)
CAS # 121-79-9
Density 1.21 (NTP, 1992)
EC Number 204-498-2
Extinction Coefficient EmM = 10.2 (272 nm, 1 M HCl) (Lit.)
Flash Point 368° F (NTP, 1992)
Format Powder
Hazard Statements H302-H317
Melting Point 302° F (NTP, 1992)
Molecular Formula C10H12O5
Molecular Weight 212.201 g/mol
Personal Protective Equipment Dust mask , Eyeshields, Faceshields, Gloves
pH pH = 6.3 (0.05% aqueous solution); pH = 5.9 (0.1% aqueous solution); pH = 5.7 (0.2% aqueous solution)
pKa 8.11 (Lit.)
RTECS Number LW8400000
Safety Symbol GHS07
Solubility less than 1 mg/mL at 68° F (NTP, 1992)
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Density 7.3 (NTP, 1992) (Relative to Air)
Vapor Pressure 2.6X10-7 mm Hg at 25 deg C (est)