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Specifications
| SKU | 0215805625 |
| Application Notes | Flumequine is a fluoroquinolone synthetic chemotherapeutic antibiotic. Flumequine is used to study processes that affect mammalian chromosome and DNA unwinding at the level of gyrase/topoisomerases. It is used to study hepatocarcinogenicity and DNA damage in mice and the mechanisms of quinolone resistance. |
| Base Catalog Number | 15805625 |
| Beilstein Registry Number | 490724 |
| Biochemical Physiological Actions | Flumequine inhibits topoisomerases, which are needed for the transcription and replication of bacterial DNA. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited . |
| CAS # | 42835-25-6 |
| EC Number | 255-962-6 |
| Melting Point | 253-255 °C (Lit.) |
| Molecular Formula | C14H12FNO3 |
| Molecular Weight | 261.25 |
| Pack Size | 25 g |
| Personal Protective Equipment | Eyeshields, Gloves, respirator filter |
| Solubility | Practically insoluble in water, slightly soluble in ethanol, in methanol, acetone and in chloroform, insoluble in benzene, soluble in alkaline solution, soluble in 1M ammonium hydroxide (200 mg/ 4 mL-clear faint yellow solution). |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
Documents
Datasheet
Datasheet