Product Description
Sorbitol Dehydrogenase
Application Notes
Sorbitol dehydrogenase has been used in a study to investigate osmotic stress induced oxidative damage as a possible mechanism of cataract formation in diabetes.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Cabrohydrate metabolism
Specifications
| SKU | 0215664205 |
| Alternate Names | L-Iditol dehydrogenase; Polyol dehydrogenase; L-Iditol: NAD+ 5-oxidoreductase; EC 1.1.1.14; SDH |
| Application Notes | Sorbitol dehydrogenase has been used in a study to investigate osmotic stress induced oxidative damage as a possible mechanism of cataract formation in diabetes. |
| Base Catalog Number | 15664205 |
| Biochemical Physiological Actions | Activity of sorbitol dehydrogenase increases in diabetic animals. |
| CAS # | 9028-21-1 |
| Format | Powder |
| Hazard Statements | H317 |
| Pack Size | 5 mg |
| Personal Protective Equipment | Eyeshields, Gloves, respirator filter |
| Source | Sheep Liver |
| Specific Activity | ≥20 u/mg protein |
| Specificity | Reduces L-iditol to L-sorbose. Also acts on D-glucitol and other closely related sugar alcohols. Allows the reduction of ketones to polyols. The reduction of D-fructose is favored. However; alkaline pH shifts the equilibrium in favor of sorbitol oxidation. SDH does not oxidize erythritol; D- or L-arabitol; D-iditol; D-mannitol or inositol. It will not reduce D-tagatose; D-mannoheptulose; D-glucose; DL-glyceraldehyde; pyruvate; 2-oxolutarate or acetaldehyde. |
| Unit Definition | One unit will convert 1.0 umole of D-fructose to D-sorbitol per minute at pH 7.6 at 25 °C. |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
Documents
Certificate of Analysis (COA)
![MP COA [02156642] lot ID: U1123278898](https://www.mpbio.com/static/version1781680552/frontend/Mpbio/luma/en_US/images/document.png "MP COA [02156642] lot ID: U1123278898")
Datasheet
Datasheet
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