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Product Description
Phenylmethylsulfonyl-Fluoride(Pmsf)
Application Notes
Phenylmethylsulfonyl Fluoride inhibits serine proteases such as trypsin and chymotrypsin. Also inhibits cysteine proteases (reversible by reduced thiols) and mammalian acetylcholinesterase but not those from fish sources.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Inhibitor of trypsin; chymotrypsin and protease
Specifications
| SKU | 04800263 |
| Alternate Names | α-Toluenesulfonyl fluoride; Benzylsulfonyl fluoride; PMSF; Phenylmethanesulfonyl fluoride |
| Application Notes | Phenylmethylsulfonyl Fluoride inhibits serine proteases such as trypsin and chymotrypsin. Also inhibits cysteine proteases (reversible by reduced thiols) and mammalian acetylcholinesterase but not those from fish sources. |
| Base Catalog Number | 800263 |
| Beilstein Registry Number | 2088311 |
| Biochemical Physiological Actions | Administration of PMSF produces analgesia unrelated to its anticholinesterase effect, and prolongs the analagesic effect of centrally administered β-endorphin. |
| CAS # | 329-98-6 |
| EC Number | 206-350-2 |
| Format | Needle-shaped Crystals |
| Half Life | 1 hr. at pH 7.5(Lit.) |
| Hazard Statements | H301-H314 |
| Molecular Formula | C7H7FO2S |
| Molecular Weight | 174.189 g/mol |
| Pack Size | 5 g |
| Personal Protective Equipment | Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator cartridge, respirator filter |
| Protein or Enzyme Type | Activators, Inhibitors & Substrates |
| Purity | ≥98% |
| RTECS Number | XT8040000 |
| Safety Symbol | GHS05, GHS06 |
| Typical Working Concentration | Effective concentration 15 to 175 ug/mL (Lit.) |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
Documents
![MP COA [800263] lot ID: 1344B](https://www.mpbio.com/static/version1660036767/frontend/Mpbio/default/en_US/images/document.png "MP COA [800263] lot ID: 1344B")