Pyrazinamide

Name: Pyrazinamide
SKU: 02195473-CF

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Key features and details

Pyrazinamide

Synonyms

Pyrazinecarboxamide; Pyrazinoic acid amide

CAS Number:

98-96-4

Molecular Formula:

C5H5N3O

Molecular Weight:

123.115 g/mol

Beilstein Registry Number:

112306

EC Number:

202-717-6

MDL Number:

MFCD00006132

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Product Description

Pyrazinamide

Application Notes

Pyrazinamide is used therapeutically as an antitubercular agent. Pyrazinamide is used to form polymeric copper complexes, create pyrazine carboxamide scaffolds useful as FXs inhibitors, and as a component of mycobacteria identification kits. It is used to study liver toxicity prevention and mechanisms of resistance.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antitubercular agent

Specifications

SKU	02195473-CF
Alternate Names	Pyrazinecarboxamide; Pyrazinoic acid amide
Applications	Antitubercular agent
Application Notes	Pyrazinamide is used therapeutically as an antitubercular agent. Pyrazinamide is used to form polymeric copper complexes, create pyrazine carboxamide scaffolds useful as FXs inhibitors, and as a component of mycobacteria identification kits. It is used to study liver toxicity prevention and mechanisms of resistance.
Base Catalog Number	195473
Beilstein Registry Number	112306
Biochemical Physiological Actions	The active moiety of pyrazinamide is pyrazinoic acid (POA). POA is thought to disrupt membrane energetics and inhibit membrane transport function at acid pH in Mycobacterium tuberculosis. Iron enhances the antituberculous activity of pyrazinamide. Pyrazinamide and its analogs have been shown to inhibit the activity of purified FAS I.
Boiling Point	SUB (NTP, 1992)
CAS #	98-96-4
EC Number	202-717-6
Format	Powder
Melting Point	376 to 379° F (NTP, 1992)
Molecular Formula	C5H5N3O
Molecular Weight	123.115 g/mol
Personal Protective Equipment	Eyeshields, Gloves, respirator filter
pH	Aqueous solutions are neutral
Purity	≥99%
RTECS Number	UQ2275000
Solubility	>18.5 [ug/mL]
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.