FastPrep Homogenizers and Lysis system
MP Bio offers a complete range of bead beating, cell lysis and tissue homogenization solutions to suit your sample preparation needs.
Utilizing bead-beating technology, the FastPrep system provides complete lysis of virtually any sample type and is suitable in a variety of applications from soil analysis to forensics. Mechanical tissue homogenization with the FastPrep system enables the isolation of DNA, RNA, proteins, and other small molecules while eliminating the need for chemicals or enzymes, which can inhibit downstream processes.
FastPrep® Instrument Trial
This free trial offer allows you to try a FastPrep® instrument in your lab for sample preparation prior to purchasing.
Choose the right FastPrep homogenizer for your needs
| Image | Description | Sample Capacity | Adapters | Tube Compatability | Cryogenic Lysis | Interface | Pre-Defined Protocols | User Defined Protocols | Min Speed | Max Speed | Acceleration | Deceleration | Motion | Typical Lysis Time (s) | Dimensions | Weight | Loudness | Power requirements | 110/230V switch | Links |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SuperFastPrep-2™ |
High-Performance, Handheld Field Lysis system | 2 | No | 2 ml | No | Manual button | No | No | 500 CPM | 4,400 CPM | Ø 500 G | NA | Reciprocating | 5 | 13"L x 3.4"W x 4.6"H | 2.2 kg | < 100 dB | 90-240 V for battery charger, cordless operation | Battery loader spec | |
FastPrep-24™ Classic |
Bench-Top Bead Beating Lysis System | Up to 48 | Interchangeable | 2 ml, 4.5 ml, 15 ml, 50 ml | Yes | LCD/membrane keyboard | No | 5 | 4.0 m/s | 6.5 m/s | < 2 sec to max | < 2 sec to stop | Figure 8 tridimentional | 40 | 465 mm (H) x 437 mm (W) x 332 mm (L) | 17.5 kg (45 lb) | 70 dB | 90-250 V AC, 50/60 Hz, 1,200 W | Automatic | |
FastPrep-24™ 5G |
Advanced Bench-Top Bead Beating Lysis System | Up to 48 | Interchangeable | 2 ml, 4.5 ml, 15 ml, 50 ml | Yes | Touch Screen | 72 | 12 | 4.0 m/s | 10.0 m/s | < 2 sec to max | < 2 sec to stop | Figure 8 tridimentional | 20 | 490 mm (H) x 472 mm (W) x 385 mm (L) | 23.6 kg (52 lb) | < 70 dB | 120 VAC/60 Hz, 500W; 230 VAC/50 Hz, 500 W |
Automatic | |
FastPrep 96™ |
High Throughput, High-Performance Bead Beating Lysis System | Up to 96 | Interchangeable | 2 ml, 4.5 ml, 15 ml, 50 ml, 96 plate, 250 ml | Yes | VFD/ industrial buttons | No | 1 | 800 RPM | 1800 RPM | < 2 sec to max | < 2 sec to stop | Vertical Linear | 40 | 700mm (H) x 440mm (W) x 660mm (L) | 49 kg (108 lb) | < 65 dB | 110 VAC/60 Hz, 5.2A; 220 VAC/50 Hz, 2.6A |
Automatic |
Explore All FastPrep Instruments & Accessories
FastPrep-24™ 5G Instrument
A versatile sample disruption instrument designed to quickly and efficiently homogenize, grind, or lyse biological samples. A completely self-contained system, it eliminates the risk of cross-contamination and time-consuming clean-up associated with manual lysis methods.
FastPrep-24™ Classic Instrument
Grind, homogenize and lyse any sample in 40 seconds or less with the FastPrep-24 Classic. It has been cited in over 8,500 citations, providing researchers consistent results and high yields as a reliable and affordable benchtop instrument.
FastPrep-96™ Instrument
The FastPrep-96 delivers superior performance, speed and reproducibility with high-throughput capabilities – process up to 192 samples simultaneously in 2 x 96 deep well plates. The true linear motion of FastPrep-96 eliminates the need to re-orient plates mid-cycle.
SuperFastPrep-2™
A portable, hand-held sample disruption instrument designed to quickly and efficiently homogenize, grind, or lyse biological and environmental samples. It can be used at remote locations and in most weather conditions for the immediate collection, processing and preservation of samples.
FastPrep Lysing Matrix tubes
The FastPrep Lysing Matrices come in 16 unique matrix compositions to ensure leak and contamination-free homogenization of any sample type without DNA/RNA shearing. FastPrep Lysing Matrices are critical components of the FastPrep sample preparation system.
FastPrep Adapters
MP Bio offers the widest selection of adapters to best meet your sample preparation needs. Adapters allow for sample sizes ranging from 2 mL to 50 mL tubes, 250 mL bottles and 96-deep well plates and are built for durability in ambient and cryogenic conditions.
Frequently Asked Questions
Q: Can I use and leave my FastPrep in a cold room at 4 °C for a long period of time?
A: The operating temperature range for the FastPrep Instruments is from 2 – 48 °C so storing at 4 °C is not a problem. MP Bio has thoroughly tested using and storing a FastPrep in a cold room and have confirmed with other customers. It was built to be used at room temperature so there is a risk of condensation of water and impacting the effect of the motor oil.
Q: Can I use other tubes than the FastPrep Lysing Matrix tubes with my FastPrep Instrument?
A: No. MP Bio has tested a variety of tubes that either did not fit the FastPrep Instrument or were damaged by the vigorous shaking necessary for grinding. The MP Biomedicals Lysing Matrix tubes will provide the best and most accurate results and are the best available for use.
Q: Should I balance the tubes when using a FastPrep Instrument?
A: You do not need to balance the tubes when using a FastPrep-24 Classic and FastPrep-24 5G instruments. They are not a centrifuge and you do need to balance the tubes on adapters.
You do need to balance the tubes when using the FastPrep-96.
Q: With my new FastPrep 24 I received a set of 8 springs. How do I know when to use them?
A: Each instrument is equipped with two springs. We include these spare springs to prevent delays that could be caused from a spring break. We recommend users change them approximately every two years depending on the frequency and intensity of use of the instrument. The procedure to replace a spring is in the user manual.
Q: There is nothing on the display of the FastPrep-24 Classic or FastPrep-24 5G but it is powered and turned on?
A:The device is shipped with the ‘Emergency Stop’ engaged for safety and will not run until disengaged. Disengage the ‘Emergency Stop’ by turning clockwise until it pops out.
Q: There was a power outage during a run with my FastPrep-24 5G and I need to get my samples back as soon as possible. How do I do that?
A: To open the ‘Dome’, pull the ‘Dome Release Cable’ on back plate of device to release the ‘Dome Latch’.
Q: What is the equivalence of m/s from FastPrep and rpm for other bead beaters?
A: The rpm value refers to the rotation per minutes and the motion on FastPrep-24 is not a rotating motion. The MP Bio FastPrep instrument has a tridimensional motion (8 motion) and m/sec refers to the distance done by the sample or bottom during one second. To convert from rpm to m/s, compare the number of turns carried out by the axis of the engine against the meter per second below.
Motor speed at 4.m/s is between 3400 to 4100 rpm
Motor speed at 6.5 m/s is between 3700 to 4500 rpm
This depends on the adapter used and the distance from tubes to the axis of the FastPrep.
Q: My tubes leaked while using the FastPrep Instrument. Why?
A: If the FastPrep Instrument is run at speeds higher than recommended, it is possible that the heavy ceramic spheres and cylinders can either crack the tubes or weaken the bottoms so that they break when spun. If working with samples that are difficult to lyse, run the FastPrep Instrument at the highest recommended speed for 20-30 seconds, place the tubes in an ice bath to cool, then process the samples again in the FastPrep Instrument. This can be repeated until lysis is complete.
The tubes may also leak if there less than a 0.5 mL empty space inside the tube. During mechanical lysis, the temperature inside the tube rises, increasing the pressure, which can lead to tube failure.
Q: Is it possible to isolate virus particles from animal tissues with the FastPrep System?
A: Yes, using Lysing Matrix A tubes to induce the lysis of viruses together with the animal cells. When the garnet sand is removed and the homogenization process is performed with one ceramic bead, the animal cells are lysed but not the virus, keeping the protein capsid intact. To perform this, set the FastPrep Instrument at a speed of 6.5 m/s for 20 seconds. Reference: Klempa B. et al. (2005) J.Clin.Microbiol. Vol 43(6); 2756-2763.
Q: What setting is recommended for a successful homogenization of skin samples?
A: Use Lysing Matrix A and do 4 runs of 20 seconds on the FastPrep Instrument at a speed of 6.0 m/s. Incubate samples on ice for 2 minutes between each run.
Bead Beating Resources
Sample Preparation Brochure
A comprehensive solution from tissue homogenization through to purification of DNA, RNA and proteins.
Environmental Brochure
From sample preparation to molecular analysis of environmental samples including soil, plant tissue and feces.
Challenges in Plant Research
Discover our range of reagents and instruments designed to meet the challenges of plant research.
Have an old FastPrep Instrument that you’d like to trade in?
Upgrade the performance of your homogenization with the FastPrep-24™, FastPrep-24™ 5G or FastPrep-96™and save by trading-in your old instruments. We accept all types of sample preparation instruments including broken instruments, competitor instruments, and damaged equipment.
