Phorbol 12-myristate 13-acetate, molecular biology reagent, ~99%

Name: Phorbol 12-myristate 13-acetate, molecular biology reagent, ~99%
SKU: 02194804-CF

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SKU: 02194804-CF

Key features and details

Phorbol 12-Myristate 13-Acetate

Synonyms

Phorbol Myristate Acetate; Phorbol Acetate Myristate; PMA; TPA; 12-O-Tetradecanoyl-phorbol 13-acetate; 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate

CAS Number:

16561-29-8

Molecular Formula:

C36H56O8

Molecular Weight:

616.836 g/mol

Beilstein Registry Number:

2407201

MDL Number:

MFCD00036736

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Product Description

Phorbol 12-Myristate 13-Acetate

Application Notes

PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Potent tumor promoter

Specifications

SKU	02194804-CF
Alternate Names	Phorbol Myristate Acetate; Phorbol Acetate Myristate; PMA; TPA; 12-O-Tetradecanoyl-phorbol 13-acetate; 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate
Application Notes	PMA activates Ca2+- ATPase and potentiates forskolin-induced cAMP formation. It has been shown to inhibit apoptosis induced by the Fas antigen, but PMA induces apoptosis in HL-60 promyelocytic leukemia cells.
Base Catalog Number	194804
Beilstein Registry Number	2407201
Biochemical Physiological Actions	Potent tumor promoter; activates protein kinase C in vivo and in vitro.
CAS #	16561-29-8
Grade	Molecular Biology Grade
Hazard Statements	H315
Melting Point	162° F (NTP, 1992)
Molecular Formula	C36H56O8
Molecular Weight	616.836 g/mol
Personal Protective Equipment	Dust mask, Eyeshields, Gloves
Purity	99%
RTECS Number	QH4377000
Safety Symbol	GHS07
Solubility	Practically insoluble (NTP, 1992)
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure	1.8X10-17 mm Hg at 25 deg C (est)