Amikacin, phytopure™

Name: Amikacin, phytopure™
SKU: 02150342-CF

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SKU: 02150342-CF

Key features and details

CAS Number: 35717-28-5

Synonyms

1-N-[L(-)-4-Amino-2-hydroxy-butyryl] kanamycin A; O-3-Amino-3-deoxy-a -D-glucopyranosyl-(1 ---> 6)-O-6-amino-6-deoxy-a-D-glucopyranosyl-(1 ---> 4)]- N1 -(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-D-streptamine; Lukadin

CAS Number:

37517-28-5

Molecular Formula:

C₂₂H₄₃N₅O₁₃

Molecular Weight:

585.60

Beilstein Registry Number:

1445422

EC Number:

253-538-5

MDL Number:

MFCD11045969

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Product Description

From Kanamycin A. An amino-glycoside antibiotic that works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth. It is effective against gram-negative bacteria, fungi and mycobacteria.

Application Notes

Amikacin is most often used for treating infections with multidrug resistant Gram negative bacteria such as Pseudomonas aeruginosa, Acinetobacter, and Enterobacter.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic

Specifications

SKU	02150342-CF
Alternate Names	1-N-[L(-)-4-Amino-2-hydroxy-butyryl] kanamycin A; O-3-Amino-3-deoxy-a -D-glucopyranosyl-(1 ---> 6)-O-6-amino-6-deoxy-a-D-glucopyranosyl-(1 ---> 4)]- N1 -(4-amino-2-hydroxy-1-oxobutyl)-2-deoxy-D-streptamine; Lukadin
Application Notes	Amikacin is most often used for treating infections with multidrug resistant Gram negative bacteria such as Pseudomonas aeruginosa, Acinetobacter, and Enterobacter.
Base Catalog Number	150342
Beilstein Registry Number	1445422
Biochemical Physiological Actions	Amikacin prevents bacterial protein synthesis by binding to the 30S ribosome subunit and inducing mRNA misreading. It interferes with the translocation of tRNA from the A-site to the P-site.
CAS #	37517-28-5
EC Number	253-538-5
Melting Point	203-204 °C
Molecular Formula	C₂₂H₄₃N₅O₁₃
Molecular Weight	585.60
Optical Rotation	+100.5°
Personal Protective Equipment	Eyeshields, Gloves,respirator filter
Potency	~900 µg/mg
RTECS Number	WK1955000
Solubility	Water Solubility185000 mg/L (at 25 °C)
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure	5.79X10-28 mm Hg at 25 deg C (est)