Product Description
Adenosine
Application Notes
Adenosine is active in cardiovascular disorders. It is indicated in cases of angina pectoris on account of its property of increasing the coronary output and in cases of hypertension on account of its vasodilator action. It is also active on the peripheral circulation, dilating the capillary vessels. It has also been recommended in the treatment of agranulocytosis. It induces apoptosis in human leukemia HL-60 cells and also has anti-arrhythmic properties.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Treatment of cardiovascular disorders and agranulocytosis
Specifications
| SKU | 02100199-CF |
| Alternate Names | 9- β-D-Ribofuranosyladenine; Adenine riboside; Adenine-9-β-D-ribofuranoside |
| Application Notes | Adenosine is active in cardiovascular disorders. It is indicated in cases of angina pectoris on account of its property of increasing the coronary output and in cases of hypertension on account of its vasodilator action. It is also active on the peripheral circulation, dilating the capillary vessels. It has also been recommended in the treatment of agranulocytosis. It induces apoptosis in human leukemia HL-60 cells and also has anti-arrhythmic properties. |
| Base Catalog Number | 100199 |
| Beilstein Registry Number | 93029 |
| Biochemical Physiological Actions | Endogenous neurotransmitter at adenosine receptors. Cardioprotective effects may relate to activation of A1 adenosine receptors. The antiplatelet and anti−inflammatory actions of adenosine appear to be mediated via the A2 adenosine receptor. In contrast, adenosine appears to be a pro-inflammatory mediator in asthma and chronic obstructive pulmonary disease (COPD). |
| CAS # | 58-61-7 |
| EC Number | 200-389-9 |
| Extinction Coefficient | 15.4 (259 nm in 0.01 M PO4, pH 7) |
| Format | Powder, Free Base |
| Hazard Statements | H302-H313 |
| Melting Point | 500 to 518° F (NTP, 1992) |
| Molecular Formula | C10H13N5O4 |
| Molecular Weight | 267.245 g/mol |
| Optical Rotation | α20/D -70 °, c = 2 in 5% NaOH (lit.) |
| Personal Protective Equipment | Eyeshields, Gloves, respirator filter |
| pH | pH = 4.5-7.5 (solution of 3 mg/mL adenosine and 9 mg/mL <a class="pubchem-internal-link CID-5234" href="https://pubchem.ncbi.nlm.nih.gov/compound/sodium%20chloride">sodium chloride</a> in <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/water">water</a>) |
| Purity | ≥98% |
| Refractive Index | n20D 1.91 (Lit.) |
| RTECS Number | AU7175000 |
| Solubility | >40.1 [ug/mL] |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
| UV Visible Absorbance | λmax (1N HCl)-255 - 260 nm OD250/OD260 - 0.80 - 0.90 OD280/OD260 - 0.17 - 0.24 |
| Vapor Pressure | 6.0X10-15 mm Hg at 25 deg C (est) |
Documents
Certificate of Analysis (COA)
![MP COA [100199] lot ID: M9375](https://www.mpbio.com/static/version1744790984/frontend/Mpbio/default/en_US/images/document.png "MP COA [100199] lot ID: M9375")
Datasheet
Datasheet