Streptokinase

S$88.97

Key features and details

Streptokinase catalyzes hydrolysis of amide linkages

SKU: 02101114-CF

Synonyms

Streptokinase from Streptococcus hemolyticus; Arvelysin; Kabikinase; Streptase; Streptococcal firbinoysin

CAS Number:

9002-01-1

Molecular Weight:

47400 (Lit.)

EC Number:

232-647-1

MDL Number:

MFCD00082037

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Product Description

Streptokinase catalyzes hydrolysis of amide linkages. Forms a 1:1 complex with plasminogen which is then converted to streptokinase-plasmin. Both streptokinase-plasminogen and streptokinase-plasmin complexes can activate plasminogen. As a result of its interaction with human or rabbit plasminogen, streptokinase undergoes specific fragmentation.

Application Notes

Streptokinase is commonly used as a thrombolytic agent in the therapy of ischemic stroke. This therapy carries the important risk of intracerebral hemorrhage. Streptokinase is also used in the treatment of complicated parapneumonic effusions and empyema where adverse reactions, allergic type, are rare

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Thrombolytic agent

Specifications

SKU	02101114-CF
Alternate Names	Streptokinase from Streptococcus hemolyticus; Arvelysin; Kabikinase; Streptase; Streptococcal firbinoysin
Application Notes	Streptokinase is commonly used as a thrombolytic agent in the therapy of ischemic stroke. This therapy carries the important risk of intracerebral hemorrhage. Streptokinase is also used in the treatment of complicated parapneumonic effusions and empyema where adverse reactions, allergic type, are rare
Base Catalog Number	101114
CAS #	9002-01-1
EC Number	232-647-1
Format	Lyophilized solid
Molecular Weight	47400 (Lit.)
RTECS Number	OB8880000
Solubility	Soluble in water
Source	Lancefield group C strain of Streptococcus
Specific Activity	≥5,000 units/mg dry weight
Unit Definition	One unit is defined as the amount of enzyme that will liquefy a standard clot of fibrinogen, plasminogen and thrombin in 10 minutes at 37 °C and pH 7.
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.