Caerulein, sulfated

Name: Caerulein, sulfated
SKU: 02152860-CF
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SKU: 02152860-CF

Key features and details

Caerulein, Sulfated

Synonyms

pyroGlu-Gln-Asp-Tyr[SO3H]-Thr- Gly-Trp-Met-Asp-Phe-NH2; Caerulein Sulfated; Cerulein; Ceruletide; [Tyr(SO3H)4]Caerulein

CAS Number:

17650-98-5

Molecular Formula:

C58H73N13O21S2

Molecular Weight:

1352.412 g/mol

Beilstein Registry Number:

5422487

MDL Number:

MFCD00076478

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Product Description

Caerulein, Sulfated

Application Notes

Caerulein is used to study cell signaling mediated by NF-kappaB upregulation of proteins such as intercellular adhesion molecule-1(ICAM-1) and inflammation related molecules such as NADPH oxidase and Janus kinase signal transducer. It prevents gall bladder pain, renal colic, and the pain of intermittent claudication.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Used to study cell signaling mediated by NF-kappaB upregulation of proteins such as intercellular adhesion molecule-1(ICAM-1) and inflammation related molecules such as NADPH oxidase and Janus kinase signal transducer

Specifications

SKU	02152860-CF
Alternate Names	pyroGlu-Gln-Asp-Tyr[SO3H]-Thr- Gly-Trp-Met-Asp-Phe-NH2; Caerulein Sulfated; Cerulein; Ceruletide; [Tyr(SO3H)4]Caerulein
Application Notes	Caerulein is used to study cell signaling mediated by NF-kappaB upregulation of proteins such as intercellular adhesion molecule-1(ICAM-1) and inflammation related molecules such as NADPH oxidase and Janus kinase signal transducer. It prevents gall bladder pain, renal colic, and the pain of intermittent claudication.
Base Catalog Number	152860
Beilstein Registry Number	5422487
Biochemical Physiological Actions	It is seen as an antagonist of endogenous opioids.
CAS #	17650-98-5
Format	Powder
Molecular Formula	C58H73N13O21S2
Molecular Weight	1352.412 g/mol
Personal Protective Equipment	Eyeshields, Gloves, respirator filter
Preparation Method	The peptide is to be dissolved in distilled, oxygen free or preferable sterile oxygen free water first. The concentration should be high enough to allow addition of buffer after the products is dissolved completely. If necessary diluted acetic acid or ammonium hydroxide, app. 1%, can be added to help solubilize the peptide. In those rare cases where solubilization is still not achieved, the solution may be sonicated briefly (up to 10 min, temperature shouldn't rise over 30-40 °C). In order to avoid serious solubility problems, buffer or saline should be added after the peptide is fully in solution.
Solubility	1.16e-02 g/L
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.