Paxilline, 5 mg

Paxilline is a fungal tremorgenic mycotoxin which possesses potent excitatory action on acetylcholine release from nerve terminals. It specifically inhibits smooth muscle high conductance Ca²⁺ activated K⁺ channels, as well as, entrances [125]-charybotoxin binding to these channels.

Usage Statement

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Key Applications

Selective blocker of high-conductance Ca2-activated (Maxi-K) potassium channels