4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride
SKU: 02193503-CF
4-(2-Aminoethyl)Benzenesulfonyl Fluoride Hydrochloride
Application Notes
The lower molecular weight and toxicity of AEBSF relative to PMSF and related organophosphate inhibitors, make this inhibitor well suited for blocking trypsin-like activities in tissue culture media as well as in large scale purification of recombinant proteins , susceptible to proteolysis
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Inhibitor | Serine Protease Inhibitors | Trypsin Inhibitors
| SKU | 02193503-CF |
| Alternate Names | AEBSF; 4-(2-Aminoethyl)-Benzenesulfonyl Fluoride Hydrochloride; p-Aminoethylbenzenenesulfonyl fluoride |
| Application Notes | The lower molecular weight and toxicity of AEBSF relative to PMSF and related organophosphate inhibitors, make this inhibitor well suited for blocking trypsin-like activities in tissue culture media as well as in large scale purification of recombinant proteins , susceptible to proteolysis |
| Base Catalog Number | 193503 |
| Beilstein Registry Number | 7604627 |
| Biochemical Physiological Actions | Irreversible serine protease inhibitor. Inhibition constants are similar to those of PMSF and DFP. AEBSF has been shown to inhibit trypsin, chymotrypsin, plasmin kallikrein and thrombin. As an alternative to PMSF and DFP, AEBSF offers lower toxicity, improved solubility in water and improved stability in aqueous solutions. |
| CAS # | 30827-99-7 |
| Format | White powder |
| Hazard Statements | H314 |
| Molecular Formula | C8H10FNO2S • HCl |
| Molecular Weight | 239.689 g/mol |
| Purity | ≥97% |
| Safety Symbol | GHS05 |
| Storage | -20 °C |
| Typical Working Concentration | AEBSF has been used in cell culture in concentrations of up to 0.25 mM. |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |