Tamoxifen

Name: Tamoxifen
SKU: 02156738-CF
Price: 110.3 NZD

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SKU: 02156738-CF

Key features and details

Tamoxifen

Synonyms

[Z]-1-[p-Dimethylaminoethoxyphenyl]-1,2-diphenyl-1-butene; (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine; ICI 47699; trans-Tamoxifen; Z-Tamoxifen; (Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethylamine; trans-1-(p-b- Dimethylaminoethoxyphenyl)-1,2-diphenylbut-1-ene citrate

CAS Number:

10540-29-1

Molecular Formula:

C26H29NO

Molecular Weight:

371.524 g/mol

EC Number:

234-118-0

MDL Number:

MFCD00010454

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Product Description

Tamoxifen

Application Notes

Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antifungal | Antineoplastic | Immunosuppressive Antibiotics

Specifications

SKU	02156738-CF
Alternate Names	[Z]-1-[p-Dimethylaminoethoxyphenyl]-1,2-diphenyl-1-butene; (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine; ICI 47699; trans-Tamoxifen; Z-Tamoxifen; (Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethylamine; trans-1-(p-b- Dimethylaminoethoxyphenyl)-1,2-diphenylbut-1-ene citrate
Application Notes	Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation
Base Catalog Number	156738
Biochemical Physiological Actions	Tamoxifen is a Protein kinase C inhibitor. It induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.
CAS #	10540-29-1
EC Number	234-118-0
Hazard Statements	H350-H360-H362
Melting Point	97 °C
Molecular Formula	C26H29NO
Molecular Weight	371.524 g/mol
Personal Protective Equipment	Eyeshields, full-face particle respirator, Gloves, respirator cartridge , respirator filter, respirator cartridges
pKa	approximately 8.85; approximately 6.9 (in Triton® X-100)
RTECS Number	KR5919600
Safety Symbol	GHS08
Solubility	2.6 [ug/mL]
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure	3.46X10-8 mm Hg at 25 deg C (est)