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Q-VD-OPh

Q-VD-OPh

NZ$509.90
Q-Vd-Oph

SKU: 03OPH109-CF

Synonyms
Q-Val-Asp-OPH; Q-VD-OPH; Quinoline-Val-Asp-CH2-O-Ph
CAS Number:
1135695-98-5
Molecular Formula:
C26H25F2N3O6
Molecular Weight:
513.498 g/mol
Product Description

Q-Vd-Oph

Application Notes

Q-VD-OPh is a cell-permeable, irreversible inhibitor of caspase activity (Philipp J. Jost,2009). The "OPH" trap provides these important features Nontoxic (preliminary study showed no evidence of toxicity in mice injected intraperitoneally with more than 1000 mg/kg) and Potency (Our new caspase inhibitors show significant improvement in potency. IC50 values against purified caspases are now in the nanomolar range. In an in vitro cell based assay, greater than 90% inhibition of apoptosis was achieved). Note: Optimal dilutions should be determined by the laboratory for each specific applications.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Inhibitor | Caspase Inhibitor / Apoptosis Inhibitor

Specifications
SKU 03OPH109-CF
Alternate Names Q-Val-Asp-OPH; Q-VD-OPH; Quinoline-Val-Asp-CH2-O-Ph
Application Notes Q-VD-OPh is a cell-permeable, irreversible inhibitor of caspase activity (Philipp J. Jost,2009). The "OPH" trap provides these important features Nontoxic (preliminary study showed no evidence of toxicity in mice injected intraperitoneally with more than 1000 mg/kg) and Potency (Our new caspase inhibitors show significant improvement in potency. IC50 values against purified caspases are now in the nanomolar range. In an in vitro cell based assay, greater than 90% inhibition of apoptosis was achieved). Note: Optimal dilutions should be determined by the laboratory for each specific applications.
Base Catalog Number OPH109
CAS # 1135695-98-5
Format Off white semi solid
Molecular Formula C26H25F2N3O6
Molecular Weight 513.498 g/mol
Purity HPLC > 95%
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Documents

Certificates of Analysis

Certificates of Analysis
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Certificates of Analysis
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Certificates of Analysis
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Certificates of Analysis
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Certificates of Analysis
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Certificates of Analysis
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Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)
Certificates of Analysis
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Certificates of Analysis
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Certificates of Analysis
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Datasheets

Datasheets
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Material Safety Data Sheet

Material Safety Data Sheet
English (United States)
Material Safety Data Sheet
English (United States)