Product Description
Streptomycin Sulfate
Application Notes
Streptomycin Sulfate is used to inhibit bacterial protein synthesis at the level of initiation inhibition. It inhibits gram-negative and gram-positive bacteria.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Antibiotic
Specifications
SKU | 02100556-CF |
Alternate Names | Streptomycin Sesquisulfate; O-2-Deoxy-2-(methylamino)-a-L- glucopyranosyl-(1->2)-O-5-deoxy-3-C-formyl-a-L- lyxofuranosyl- (1->4)- N,N'- bis(aminoiminomethyl)-D-streptamine; Streptomycin A |
Application Notes | Streptomycin Sulfate is used to inhibit bacterial protein synthesis at the level of initiation inhibition. It inhibits gram-negative and gram-positive bacteria. |
Base Catalog Number | 100556 |
Beilstein Registry Number | 3894995 |
Biochemical Physiological Actions | Mode of Action: Inhibits prokaryote protein synthesis. Binds to S12 protein of 30S ribosomal subunit, preventing the transition from initiation complex to chain-elongating ribosome, causing miscoding or inhibiting initiation. Mode of Resistance: Mutation in rpsL (gene for S12 ribosomal protein) prevents binding of streptomycin to ribosome. Aminoglycoside phosphotransferase also inactivates. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. |
CAS # | 3810-74-0 |
EC Number | 223-286-0 |
Format | Powder |
Half Life | half-life in plasma is about 2-4 hours |
Hazard Statements | H302-H361 |
Molecular Formula | C42H84N14O36S3 |
Molecular Weight | 1457.376 g/mol |
Optical Rotation | -77 to -79 ° (c=1% in H2O, 25 °C) (lit.) |
Personal Protective Equipment | Dust mask, Eyeshields, Faceshields, Gloves |
RTECS Number | WK4990000 |
Safety Symbol | GHS07, GHS08 |
Solubility | greater than or equal to 0.1 mg/mL at 64° F (NTP, 1992) |
Specific Activity | ≥650 u/mg |
Typical Working Concentration | Typically used at a concentration of 50-100 mg/liter |
Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
Documents
Certificate of Analysis (COA)
Datasheet
Datasheet
Safety Data Sheets
English (United States)