Guanidine thiocyanate

Name: Guanidine thiocyanate
SKU: 04820991-CF
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SKU: 04820991-CF

Key features and details

Guanidine Thiocyanate

Synonyms

Guanidinium rhodanide; Guanidinium thiocyanate

CAS Number:

593-84-0

Molecular Formula:

CH5N3 • HSCN

Molecular Weight:

118.158 g/mol

Beilstein Registry Number:

3563461

EC Number:

209-812-1

MDL Number:

MFCD00013027

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Product Description

Guanidine Thiocyanate

Application Notes

Guanidine Thiocyanate is often used in the isolation of intact ribonucleic acid to eliminate RNase activity. A 4 M solution of guanidine thiocyanate irreversibly inactivates RNase. In the presence of guanidine thiocyanate, proteins dissolve readily, cellular structures disintegrate and nucleoproteins dissociate from nucleic acids, as protein secondary structure is lost.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Strong denaturant

Specifications

SKU	04820991-CF
Alternate Names	Guanidinium rhodanide; Guanidinium thiocyanate
Application Notes	Guanidine Thiocyanate is often used in the isolation of intact ribonucleic acid to eliminate RNase activity. A 4 M solution of guanidine thiocyanate irreversibly inactivates RNase. In the presence of guanidine thiocyanate, proteins dissolve readily, cellular structures disintegrate and nucleoproteins dissociate from nucleic acids, as protein secondary structure is lost.
Base Catalog Number	820991
Beilstein Registry Number	3563461
CAS #	593-84-0
EC Number	209-812-1
Format	Crystalline Granules
Grade	Research grade
Hazard Statements	H302 + H312 + H332-H314-H412, Contact with acids liberates very toxic gas.
Molecular Formula	CH5N3 • HSCN
Molecular Weight	118.158 g/mol
Personal Protective Equipment	Dust mask, Eyeshields, Gloves
Purity	>98%
Safety Symbol	GHS05, GHS07
Sterilization of Solutions	Solutions can be sterilized by filtration using a 0.2 µm filter.
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance	OD280 (6 M aq soln): <0.5