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Tryptase (purified antigen), from human lung, 59,700 mU/mg, 10 µg

Tryptase (purified antigen), from human lung, 59,700 mU/mg, 10 µg

Packaging size: 10 µg

SKU 0857047
$281.25
In Stock
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Description

Product Description

Tryptase is a glycoprotein released from mast cells during anaphylaxis, which performs a number of functions including catalyzing the activation of complement C3, converting prostromelysin to stromelysin (MMP-3), and cleaving fibrinogen resulting in a loss of clotting potential. Human tryptase is a major secretory protease of human lung mast cells.

Application Notes

Tryptase has been used in a study that purified and characterized recombinant rat mast cell protease 7 expressed in Pichia pastoris. Tryptase has also been used in a study to investigate drug allergies in mast cell disease.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Proteomics | Used in a study to investigate drug allergies in mast cell disease

Specifications
SKU 0857047
Application Notes Tryptase has been used in a study that purified and characterized recombinant rat mast cell protease 7 expressed in Pichia pastoris. Tryptase has also been used in a study to investigate drug allergies in mast cell disease.
Base Catalog Number 57047
Concentration 0.24 mg/ml
Formulation Details Liquid | 0.05M NaOAc; pH 5.0; containing 1.0M NaCl
Pack Size 10 µg
Protein or Enzyme Type Other Proteins, Enzymes Peptides
Source Human Lung
Specific Activity 59,700 mU/mg using n-benzoyl-Phe-Val-Arg-pNA as substrate.
Uniprot Number Q15661
Unit Definition One unit will hydrolyze one μM of N-benzoyl-Phe-Val-Arg-pNA per minute at 410 nm, pH 8.3, 25 °C. The assay uses 0.1M Tris buffer, pH 8.3. E,1%,280nm=30.3
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.