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Ribostamycin sulfate salt, 100 mg
Ribostamycin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit (some work by binding to the 50S subunit), inhibiting the translocation of the peptidyl-tRNA from the A-site to the P-site and also causing misreading of mRNA, leaving the bacterium unable to synthesize proteins vital to its growth.
It is used in pharmacokinetic and nephrotoxicity studies.
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
|Alternate Names||Landamycine; Ribomycine; Ribostamin; Ribostamycin Sulfate; SF 733 Antibiotic Sulfate; Vistamycin|
|Application Notes||It is used in pharmacokinetic and nephrotoxicity studies.|
|Base Catalog Number||15654380|
|Biochemical Physiological Actions||Aminoglycosides, such as ribostamycin, bind to the bacterial 30S and 50S ribosomal subunit, which inhibits the translocation of the peptidyl-tRNA from the A-site to the P-site. This causes misreading of mRNA which makes bacteria unable to make essential proteins. It also inhibits the chaperone activity of protein disulfide isomerase (PDI).|
|Pack Size||100 mg|
|Personal Protective Equipment||Eyeshields, full-face particle respirator, Gloves, respirator cartridge, respirator filter|
|Safety Symbol||GHS07, GHS08|
|Solubility||Soluble in water (200 mg/4 mL-clear, colorless solution).|
|Usage Statement||Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.|