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Probenecid is useful as an inhibitor of the organic anion transporter.
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Inhibitor of the organic anion transporter
|Alternate Names||p-[Dipropylsulfamoyl]benzoic acid|
|Application Notes||Probenecid is useful as an inhibitor of the organic anion transporter.|
|Base Catalog Number||156370|
|Biochemical Physiological Actions||Probenecid is an inhibitor of multidrug resistance-associated proteins (Mdr-1). This compound blocks the active site of Mdr-1 and prevents cellular efflux of other active compounds, enhancing their effectiveness by allowing them to remain in the cytoplasm.|
|Melting Point||381 to 385° F (NTP, 1992)|
|Molecular Weight||285.358 g/mol|
|Personal Protective Equipment||Dust mask , Eyeshields, Gloves|
|UV Visible Absorbance||λmax (0.1 N NaOH)|