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Plasminogen

Plasminogen

Plasminogen

SKU: 02191342-CF

Synonyms
Profibrinolysin
CAS Number:
9001-91-6
EC Number:
232-641-9
MDL Number:
MFCD00131922
Product Description

Plasminogen

Application Notes

Plasminogen is a single-chain glycoprotein found in human plasma and extracellular fluid. Certain activators, such as tissue plasminogen activator (tPA), convert plasminogen to its active form, plasmin. Plasminogen has been used to study its conversion into plasmin.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Specifications
SKU 02191342-CF
Alternate Names Profibrinolysin
Application Notes Plasminogen is a single-chain glycoprotein found in human plasma and extracellular fluid. Certain activators, such as tissue plasminogen activator (tPA), convert plasminogen to its active form, plasmin. Plasminogen has been used to study its conversion into plasmin.
Base Catalog Number 191342
Biochemical Physiological Actions Plasminogen is the inactive precursor of the protease plasmin. Plasminogen is activated by the action of either tissue plasminogen activator (tPA), which primarily activates the fibrinolytic (thrombolytic) activity of plasmin, or urokinase plasminogen activator (uPA), which is associated with extracellular matrix remodeling and cell migration. Plasmin cleaves fibrin/fibrinogen and blood coagulation factors V/Va and VIII/VIIIa. It activates matrix metalloproteinases by cleaving the inactive proenzymes. It is also involved in the activation of some growth factors, such as vascular endothelial growth factor (VEGF) and transforming growth factor β (TGF-β).
CAS # 9001-91-6
EC Number 232-641-9
Format Solid
Personal Protective Equipment Eyeshields, Gloves,respirator filter
Purity ≥95%
Source Human plasma
Unit Definition the amount of enzyme which will hydrolyze 1 µmol of N-tosyl-L-arginine ester in 30 minutes at 37°C at pH 8.0.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Documents

Certificates of Analysis

Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)

Datasheets

Datasheets
English (United States)