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Phytohemagglutinin

Phytohemagglutinin

Synonyms PHA

CAS Number: 9008-97-3

EC Number: 232-718-7

SKU 02151884-CF
$52.85
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Description

Product Description

Phytohemagglutinin

Application Notes

In medicine PHA proteins are useful and are used as a mitogen to trigger T-lymphocytes cell division and to activate latent HIV-1 from human peripheral lymphocytes.The lectin has a number of effects on cell metabolism; it induces mitosis, and affects the cell membrane in regard to transport and permeability to proteins. It is used as positive control in ELIspot assay.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Agglutination

Specifications
SKU 02151884-CF
Alternate Names PHA
Application Notes In medicine PHA proteins are useful and are used as a mitogen to trigger T-lymphocytes cell division and to activate latent HIV-1 from human peripheral lymphocytes.The lectin has a number of effects on cell metabolism; it induces mitosis, and affects the cell membrane in regard to transport and permeability to proteins. It is used as positive control in ELIspot assay.
Base Catalog Number 151884
Biochemical Physiological Actions PHA consists of two molecular species, an erythroagglutinin (PHA-E) which has low mitogenic activity and high erythroagglutinin activity, and leucoagglutinin (PHA-L) which has high mitogenic and leucoagglutinating activity, but very low erythroagglutinating activity. PHA-E is not blood group specific, but agglutination can be inhibited by certain oligosaccharides. PHA-P is the protein form of PHA prior to separation and purification of erythroagglutinin and leucoagglutinin. PHA-M is the mucoprotein form. Conjugates are prepared from the corresponding purified lectins.
CAS # 9008-97-3
EC Number 232-718-7
Format Off-white Lyophilized Powder
Protein or Enzyme Type Lectins
RTECS Number TJ3470000
Source Red Kidney Beans (Phaseolus vulgaris)
Specific Activity Shows agglutination when tested with human red blood cells.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.