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Oligomycin is used as antibiotic which inhibits respiration in mitochondria. It inhibits ATP synthase by blocking its proton channel (F0 subunit), which is necessary for oxidative phosphorylation of ADP to ATP (energy production).
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|Alternate Names||Olivomycin; Aburamycin|
|Application Notes||Oligomycin is used as antibiotic which inhibits respiration in mitochondria. It inhibits ATP synthase by blocking its proton channel (F0 subunit), which is necessary for oxidative phosphorylation of ADP to ATP (energy production).|
|Base Catalog Number||151786|
|Beilstein Registry Number||7615308|
|Biochemical Physiological Actions||It inhibits mitochondrial ATPase and phosphoryl group transfer.|
|Formulation Details||A mixture of oligomycin A; B and C in an approximate ratio of 60:30:10 Oligomycin A: C45H74O11 Oligomycin B: C45H72O12 Oligomycin C: C45H74O10|
|Molecular Weight||791.076 g/mol|
|Personal Protective Equipment||Dust mask, Eyeshields, Faceshields, Gloves|