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Spermine

Spermine

$51.10

Key features and details

Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. Formed from spermidine through the addition of aminopropyl group to spermidine by spermine synthase. It is found as a polycation at physiological pH.

SKU: 02152070-CF

Synonyms
Diaminopropyltetramethylenediamine; Gerontine; Musculamine; Neuridine; N,N-bis(aminopropyl)-1,4-butanediamine; 4,9-Diaza-1,12-dodecanediamine
CAS Number:
71-44-3
Molecular Formula:
C10H26N4
Molecular Weight:
202.3
Beilstein Registry Number:
1750791
EC Number:
200-754-2
MDL Number:
MFCD00008215
Product Description

Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. Formed from spermidine through the addition of aminopropyl group to spermidine by spermine synthase. It is found as a polycation at physiological pH.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

DNA precipitation | Chromosome isolation | Crystallization of DNA

Specifications
SKU 02152070-CF
Alternate Names Diaminopropyltetramethylenediamine; Gerontine; Musculamine; Neuridine; N,N-bis(aminopropyl)-1,4-butanediamine; 4,9-Diaza-1,12-dodecanediamine
Base Catalog Number 152070
Beilstein Registry Number 1750791
Biochemical Physiological Actions Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
Boiling Point 141-142°C at 0.5 mm Hg;
CAS # 71-44-3
EC Number 200-754-2
Flash Point 110 °C / 230 °F (lit.)
Hazard Statements H314
Melting Point 28-30°C (Lit.)
Molecular Formula C10H26N4
Molecular Weight 202.3
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator ,Gloves, respirator cartridge, respirator filter
pH 11-14 (0.5% aq soln)
Purity ≥97%
RTECS Number EJ7175000
Safety Symbol GHS05
Solubility Soluble in water (1% w/v), lower alcohol, chloroform; practically insoluble in ether, benzene, petroleum ether.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Citations
Documents

Certificate of Analysis

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Datasheet

Datasheet

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