Product Description
Spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. Formed from spermidine through the addition of aminopropyl group to spermidine by spermine synthase. It is found as a polycation at physiological pH.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
DNA precipitation | Chromosome isolation | Crystallization of DNA
Specifications
SKU | 02152070-CF |
Alternate Names | Diaminopropyltetramethylenediamine; Gerontine; Musculamine; Neuridine; N,N-bis(aminopropyl)-1,4-butanediamine; 4,9-Diaza-1,12-dodecanediamine |
Base Catalog Number | 152070 |
Beilstein Registry Number | 1750791 |
Biochemical Physiological Actions | Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS). |
Boiling Point | 141-142°C at 0.5 mm Hg; |
CAS # | 71-44-3 |
EC Number | 200-754-2 |
Flash Point | 110 °C / 230 °F (lit.) |
Hazard Statements | H314 |
Melting Point | 28-30°C (Lit.) |
Molecular Formula | C10H26N4 |
Molecular Weight | 202.3 |
Personal Protective Equipment | Eyeshields, Faceshields, full-face particle respirator ,Gloves, respirator cartridge, respirator filter |
pH | 11-14 (0.5% aq soln) |
Purity | ≥97% |
RTECS Number | EJ7175000 |
Safety Symbol | GHS05 |
Solubility | Soluble in water (1% w/v), lower alcohol, chloroform; practically insoluble in ether, benzene, petroleum ether. |
Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
Citations
Documents
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