Cart
 
Inquire

Orotic acid, monohydrate

Orotic acid, monohydrate

Key features and details

Orotic Acid Monohydrate

SKU: 02102508-CF

Synonyms
2,6-Dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid; Uracil-6-carboxylic acid; Whey factor; Animal galactose factor; Oropur; Orotyl; 6-Carboxy-2,4-dihydroxypyrimidine
CAS Number:
50887-69-9
Molecular Formula:
C5H4N2O4 • H2O
Molecular Weight:
174.112 g/mol
Beilstein Registry Number:
7604036
MDL Number:
MFCD00149398
Product Description

Orotic Acid Monohydrate

Application Notes

Orotic acid (OA) may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5′-phospho-α-d-ribose 1′-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5′-monophosphate (OMP). Orotic acid is used as a starting material for the potential commercial bioproduction of uridine 5′-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. OA may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Used in study of biosynthesis of pyrimidine nucleobases

Specifications
SKU 02102508-CF
Alternate Names 2,6-Dioxo-1,2,3,6-tetrahydro-4-pyrimidinecarboxylic acid; Uracil-6-carboxylic acid; Whey factor; Animal galactose factor; Oropur; Orotyl; 6-Carboxy-2,4-dihydroxypyrimidine
Application Notes Orotic acid (OA) may be used to study the specificity and kinetics of orotate phosphoribosyltransferase (OPRT) which catalyzes the reversible phosphoribosyl transfer from 5′-phospho-α-d-ribose 1′-diphosphate (PRPP) to orotic acid (OA), forming pyrophosphate and orotidine 5′-monophosphate (OMP). Orotic acid is used as a starting material for the potential commercial bioproduction of uridine 5′-monophosphate (UMP) by microbes such as Corynebacterium ammoniagenes (ATCC 6872) or Saccharomyces cerevisiae. OA may be used to study the AMPK/SREBP-1 dependent cell signaling pathway and transcription regulation mechanisms that induce hepatic lipogenesis.
Base Catalog Number 102508
Beilstein Registry Number 7604036
CAS # 50887-69-9
Format Powder
Hazard Statements H315-H319-H335
Molecular Formula C5H4N2O4 • H2O
Molecular Weight 174.112 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Gloves
Safety Symbol GHS07
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance λ max (water) 205 nm (280 nm) ± 5 nm
Documents

Certificate of Analysis

Certificate of Analysis
Certificate of Analysis
Certificate of Analysis

Datasheet

Datasheet

Material Safety Datasheet

Material Safety Datasheet
en_AU
Material Safety Datasheet
en_CA
Material Safety Datasheet
fr_CA
Material Safety Datasheet
cn_ZH
Material Safety Datasheet
de_DE
Material Safety Datasheet
es_ES
Material Safety Datasheet
en_EU
Material Safety Datasheet
fi_FI
Material Safety Datasheet
fr_FR
Material Safety Datasheet
en_GB
Material Safety Datasheet
ja_JP
Material Safety Datasheet
es_MX
Material Safety Datasheet
no_NO
Material Safety Datasheet
pt_PT
Material Safety Datasheet
sv_SE
Material Safety Datasheet
en_US