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Sodium selenite

Sodium selenite

$66.35

Key features and details

Sodium Selenite

SKU: 02102928-CF

Synonyms
Selenious Acid Disodium Salt; Disodium selenite; Natriumselenit; Selenious acid sodium salt
CAS Number:
10102-18-8
Molecular Formula:
Na2SeO3
Molecular Weight:
172.948 g/mol
EC Number:
233-267-9
MDL Number:
MFCD00003489
Product Description

Sodium Selenite

Application Notes

Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite is included in various medium supplements for use in cell culture. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Specifications
SKU 02102928-CF
Alternate Names Selenious Acid Disodium Salt; Disodium selenite; Natriumselenit; Selenious acid sodium salt
Application Notes Sodium selenite is commonly used as a source of selenium in biological research, where selenium is an essential trace element that is normally provided by serum. Selenium is present in selenoproteins such as glutathione peroxidase and thioredoxin reductase, which contain the selenium analog of cysteine, selenocysteine. In particular, glutathione peroxidase has a role in detoxification in vivo as a scavenger of peroxides. Sodium selenite is included in various medium supplements for use in cell culture. Sodium selenite has been utilized in studies of cell proliferation and cancer research. It has been used to alter gene expression in HepG2 cells as analyzed by cDNA microarrays. Sodium selenite can inhibit zinc finger protein/DNA interactions. Sodium selenite has been shown to alter mitochondrial membrane potentials and thus potentially contribute to apoptosis.
Base Catalog Number 102928
Biochemical Physiological Actions More potent than selenomethionine in reducing carcinogenesis.
Boiling Point Decomposes (NTP, 1992)
CAS # 10102-18-8
Density 3.1 (NTP, 1992)
EC Number 233-267-9
Format Powder
Grade Cell Culture Grade
Hazard Statements H300-H317-H331-H411; Contact with acids liberates toxic gas.
Melting Point 1310° F (decomposes) (NTP, 1992)
Molecular Formula Na2SeO3
Molecular Weight 172.948 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves, Respirator cartridges
Purity ~98%
RTECS Number VS7350000
Safety Symbol GHS06, GHS09
Solubility greater than or equal to 100 mg/mL at 70.7° F (NTP, 1992)
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure less than 0.001 mm Hg at 68° F (NTP, 1992)
Citations
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