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Hemin chloride from porcine

$39.20

Key features and details

Hemin Chloride

SKU: 02198820-CF

Synonyms

Hemin Chloride; Chloroferriprotoporphyrin; Chlorohemin; Chloro(protoprophyrinato) iron (III); Ferriprotoporphyrin IX chloride; Hematin hydrochloride; Protohemin IX; (SP-5-13)-Chloro [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)- N21, N22, N23, N24] ferrate(2-) dihydrogen; Chloro [dihydrogen 3,7,12,17-tetramethyl-8,13-divinyl-2, 18-porphinedipropionato (2-)]iron; 1,3,5,8-tetramethyl-2,4-divinylporphine-6,7- dipropionic acid ferrichloride; Teichmann's crystals; Ferriheme chloride

CAS Number:

16009-13-5

Molecular Formula:

C34H32ClFeN4O4

Beilstein Registry Number:

5229914

EC Number:

240-140-1

MDL Number:

MFCD00010726

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Product Description

Hemin Chloride

Application Notes

Hemin is used in the management of porphyria attacks, particularly in acute intermittent porphyria.It may be used to study the expression and repression of heme oxygenase 1 (HO-1) as well as the activity of HO-1.Hemin is used for the following applications:• To study bacterial strains and growth conditions• Used in short-term colony assays (the culture medium consists of hemin along with other components)• Cell transfections• It may be used in ß-hematin formation assay for analyzing the inhibitory activity of MMV (Medicines for Malaria Venture) Malaria Box compounds against the formation of β-hematin.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Specifications

SKU	02198820-CF
Alternate Names	Hemin Chloride; Chloroferriprotoporphyrin; Chlorohemin; Chloro(protoprophyrinato) iron (III); Ferriprotoporphyrin IX chloride; Hematin hydrochloride; Protohemin IX; (SP-5-13)-Chloro [7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)- N21, N22, N23, N24] ferrate(2-) dihydrogen; Chloro [dihydrogen 3,7,12,17-tetramethyl-8,13-divinyl-2, 18-porphinedipropionato (2-)]iron; 1,3,5,8-tetramethyl-2,4-divinylporphine-6,7- dipropionic acid ferrichloride; Teichmann's crystals; Ferriheme chloride
Application Notes	Hemin is used in the management of porphyria attacks, particularly in acute intermittent porphyria.It may be used to study the expression and repression of heme oxygenase 1 (HO-1) as well as the activity of HO-1.Hemin is used for the following applications:• To study bacterial strains and growth conditions• Used in short-term colony assays (the culture medium consists of hemin along with other components)• Cell transfections• It may be used in ß-hematin formation assay for analyzing the inhibitory activity of MMV (Medicines for Malaria Venture) Malaria Box compounds against the formation of β-hematin.
Base Catalog Number	198820
Beilstein Registry Number	5229914
Biochemical Physiological Actions	Hemin, the oxidized version of heme, is an iron-containing prosthetic group for a diverse group of proteins. Free heme, which can be released from hemoglobin following hemolysis, is pro-inflammatory and contributes to iron-derived reactive oxygen species. Free hemin levels may be upregulated in various pathological conditions and can contribute to various inflammatory conditions including vascular disorders, renal failure, and immune-mediated disorders. Hemin may be used to study the expression and represson of heme oxygenase 1 (HO-1) as well as the activity of HO-1. Hematin is the "X factor" required to grown Haemophilus influenzae.
CAS #	16009-13-5
EC Number	240-140-1
Format	Powder
Molecular Formula	C34H32ClFeN4O4
Personal Protective Equipment	Eyeshields, Gloves,respirator filter
Preparation Method	Typically prepared by heating a hemoglobin solution with acetic acid and sodium chloride.
Source	Porcine
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.