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Product Description
Aprotinin
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Competitive serine protease inhibitor
Specifications
| SKU | 02191158-CF |
| Alternate Names | Antagosan; Anikrein; Antilysin(e); Basic pancreatic trypsin inhibitor; BPTI; Bayer A 128; Kallikrein-trypsin inactivator; Fosten; Iniprol; Kunitz protease inhibitor; Onquinin; Repulson; RP-9921; Ryker 52G; Trasylol; Triazinin; Zymofren |
| Base Catalog Number | 191158 |
| Biochemical Physiological Actions | Aprotinin is a competitive serine protease inhibitor that inhibits trypsin, chymotrypsin, kallikrein and plasmin. Aprotinin forms stable complexes with and blocks the active sites of enzymes. Binding is reversible with most aprotinin-protease complexes dissociating at pH >10 or < 3. |
| CAS # | 9087-70-1 |
| EC Number | 232-994-9 |
| Extinction Coefficient | E1% (280 nm) = 8.3 (water) |
| Format | Lyophilized powder |
| Isoelectric Point | 10.5 |
| Melting Point | >100 °C |
| Molecular Formula | C284H432N84O79S7 |
| Molecular Weight | 6511.509 g/mol |
| RTECS Number | YN5080000 |
| Source | Bovine Lung |
| Specific Activity | ~4 inhibitor u/mg |
| Sterilization of Solutions | Sterilization of solutions can be done by filtration through a 0.2 um filter. |
| Typical Working Concentration | Equimolar with protease (1-2 ug/ml) |
| Unit Definition | The quantity of protease inhibitor that has the ability to inhibit 2 Kallikrein units by 50% under optimal conditions. |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
| UV Visible Absorbance | 277 ± 5 nm (1 max water) |
Documents
![MP COA [191158] lot ID: 1286B](https://www.mpbio.com/static/version20220125073033Z/frontend/Mpbio/default/en_US/images/document.png "MP COA [191158] lot ID: 1286B")