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Papain, technical grade, >1750 USP U/mg

Papain, technical grade, >1750 USP U/mg

$140.40

Key features and details

Papain

SKU: 02102566-CF

Synonyms
Papayotin; Vegetable Pepsin; Caroid; Vermizym; Papainase
CAS Number:
9001-73-4
Molecular Weight:
226.236 g/mol
EC Number:
232-627-2
MDL Number:
MFCD00131791
Product Description

Papain

Application Notes

Papain is widely used in cell isolation. With some tissues papain has proved less damaging and more effective than other proteases. Of the enzymes used for dissociating turtle retina, papain produced the least trauma. Intact single photoreceptor cells have also been isolated from adult salamander retina with papain. Papain used to obtain high yields of viable, morphologically intact cortical neurons from postnatal rats. Used for dissociation of postnatal rat hippocampus. Papain is used with fetal as well as postnatal brain regions to provide maximal dissociation and viability of neurons. It is also used to produce Fab fragments of antibodies. In addition, papain is used in red cell serology to modify the red cell surface to enhance or destroy the reactivity of many red cell antigens. Papain is useful for platelet serology studies. Papain has also been used in the enzymatic synthesis of amino acids, peptides, and other molecules.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

For production of Fab fragments of antibodies | Used for cell dissociation

Specifications
SKU 02102566-CF
Alternate Names Papayotin; Vegetable Pepsin; Caroid; Vermizym; Papainase
Application Notes Papain is widely used in cell isolation. With some tissues papain has proved less damaging and more effective than other proteases. Of the enzymes used for dissociating turtle retina, papain produced the least trauma. Intact single photoreceptor cells have also been isolated from adult salamander retina with papain. Papain used to obtain high yields of viable, morphologically intact cortical neurons from postnatal rats. Used for dissociation of postnatal rat hippocampus. Papain is used with fetal as well as postnatal brain regions to provide maximal dissociation and viability of neurons. It is also used to produce Fab fragments of antibodies. In addition, papain is used in red cell serology to modify the red cell surface to enhance or destroy the reactivity of many red cell antigens. Papain is useful for platelet serology studies. Papain has also been used in the enzymatic synthesis of amino acids, peptides, and other molecules.
Base Catalog Number 102566
Biochemical Physiological Actions Papain is a cysteine protease that cleaves peptide bonds of basic amino acids, leucine, or glycine. It is also hydrolyzes esters and amides. Papain consists of a single polypeptide chain with three disulfide bridges and a sulfhydryl group necessary for activity of the enzyme.
CAS # 9001-73-4
EC Number 232-627-2
Extinction Coefficient 25.0 (Lit.)
Format Powder
Grade Technical Grade
Hazard Statements H315-H319-H334-H335
Isoelectric Point pH 9.6 (Lit.)
Molecular Weight 226.236 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves
RTECS Number RU4950000
Safety Symbol GHS07, GHS08
Specific Activity >1750 USP u/mg
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Documents

Certificate of Analysis

Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis

Datasheet

Datasheet

Material Safety Datasheet

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