Vitamin B12

Application Notes

Vitamin B12 plays a role in the synthesis of myelin. It is a cofactor for two enzymes, methionine synthase and L-methylmalonyl-CoA mutase. The compound is also used as an antipernicious anemia factor.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antipernicious anemia factor | Cofactor | Treatment of vitamin B12 deficiency; cyanide poisoning; and hereditary deficiency of transcobalamin II

SKU	02103271-CF
Alternate Names	Cyanocobalamin; α-(5,6-Dimethylbenzimidazolyl)cyanocobamide; CN-Cbl; Cyanocob(III)alamin
Application Notes	Vitamin B12 plays a role in the synthesis of myelin. It is a cofactor for two enzymes, methionine synthase and L-methylmalonyl-CoA mutase. The compound is also used as an antipernicious anemia factor.
Base Catalog Number	103271
Beilstein Registry Number	4122889
Biochemical Physiological Actions	Biosynthesis of the basic structure of the vitamin is accomplished only by bacteria(which usually produce hydroxocobalamin). Bacteria-derived hydroxocobalamin (OHCbl) and CNCbl are converted in humans to useful coenzyme forms to support metabolic processes such as mitochondrial methylmalonylcoenzyme A mutase conversion of methylmalonic acid (MMA) to succinate to link lipid and carbohydrate metabolism, and activation of methionine synthase, the rate limiting step in the synthesis of methionine.
Boiling Point	> 300 deg C
CAS #	68-19-9
EC Number	200-680-0
Format	Powder
Melting Point	> 300 Â°C
Molecular Formula	C63H88N14O14PCo
Molecular Weight	1355.388 g/mol
Personal Protective Equipment	Eyeshields, Gloves, respirator filter
pH	Commercially available <a class="pubchem-internal-link multiple-CIDs" href="https://pubchem.ncbi.nlm.nih.gov/compound/cyanocobalamin">cyanocobalamin</a> for injection has a pH of 4.5-7
Purity	≥96%
RTECS Number	GG3750000
Solubility	<h5 class="minor-section-title">Water Solubility</h5>12500 mg/L
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.