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Cyclophosphamide monohydrate

$52.15

Key features and details

Cyclophosphamide Monohydrate

SKU: 02150749-CF

Synonyms

Endoxan A; Cytoxan; 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide; N,N-bis(2-Chloroethyl) tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide monohydrate; 2-[bis(2-Chloroethyl) amino] tetrahydro-2H-1,3,2-oxazophosphorine 2-oxide monohydrate; 1-bis(2-Chloroethyl) amino-1-oxo-2-aza-5-oxaphosphoridin monohydrate; bis(2-Chloroethyl) phosphamide cyclic propanolamide ester monohydrate; bis(2-Chloroethyl)phosphoramide cyclic propanolamide ester monohydrate; N,N-bis(b-Chloroethyl)-N',O-propylenephosphoric acid ester diamide monohydrate; N,N-bis(b-Chloroethyl)-N',O-trimethylenephosphoric acid ester diamide monohydrate; Cyclophosphane; Cytophosphane; B-518

CAS Number:

6055-19-2

Molecular Formula:

C7H15Cl2N2O2P · H2O

Molecular Weight:

279.098 g/mol

Beilstein Registry Number:

4678992

EC Number:

200-015-4

MDL Number:

MFCD00149395

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Product Description

Cyclophosphamide Monohydrate

Application Notes

Cyclophosphamide monohydrate used for induction chemotherapy to study predictive and prognostic values of tumor MGMT gene expression, to study its effects on apoptosis and cell cycle progression and its cardiotoxicity during pretransplant conditioning in blood stem cell transplantation has been reported.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Cancer research tool

Specifications

SKU	02150749-CF
Alternate Names	Endoxan A; Cytoxan; 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide; N,N-bis(2-Chloroethyl) tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide monohydrate; 2-[bis(2-Chloroethyl) amino] tetrahydro-2H-1,3,2-oxazophosphorine 2-oxide monohydrate; 1-bis(2-Chloroethyl) amino-1-oxo-2-aza-5-oxaphosphoridin monohydrate; bis(2-Chloroethyl) phosphamide cyclic propanolamide ester monohydrate; bis(2-Chloroethyl)phosphoramide cyclic propanolamide ester monohydrate; N,N-bis(b-Chloroethyl)-N',O-propylenephosphoric acid ester diamide monohydrate; N,N-bis(b-Chloroethyl)-N',O-trimethylenephosphoric acid ester diamide monohydrate; Cyclophosphane; Cytophosphane; B-518
Application Notes	Cyclophosphamide monohydrate used for induction chemotherapy to study predictive and prognostic values of tumor MGMT gene expression, to study its effects on apoptosis and cell cycle progression and its cardiotoxicity during pretransplant conditioning in blood stem cell transplantation has been reported.
Base Catalog Number	150749
Beilstein Registry Number	4678992
Biochemical Physiological Actions	Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.
CAS #	6055-19-2
EC Number	200-015-4
Flash Point	greater than 230Â° F (NTP, 1992)
Hazard Statements	H301-H350
Melting Point	121 to 127Â° F (NTP, 1992)
Molecular Formula	C7H15Cl2N2O2P · H2O
Molecular Weight	279.098 g/mol
Personal Protective Equipment	Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator cartridge, respirator filter
Purity	≥98%
RTECS Number	RP6157750
Safety Symbol	GHS06, GHS08
Solubility	10 to 50 mg/mL at 73Â° F (NTP, 1992)
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.