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Gossypol is a poisonous pigment found in cottonseed. Its name is derived from the botanical name of the cotton plant, Gossypium L., Malvaceae.
Gossypol is potentially used as a male contraceptive by apparently inhibiting LH. The antiviral activity appears at low concentrations (up to 1 ug/mL) with a broad activity spectrum: RNA and DNA viruses, microviruses and herpes viruses.
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|Alternate Names||(±)-Gossypol from cotton seeds; 1,1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-5,5'-bis (1-methylethyl) [2,2'-binaphthalene]-8,8'-dicarboxaldehyde; 1,1',6,6',7,7'-hexahydroxy-5,5'-diisopropyl-3,3'- dimethyl [2,2'-binaphthalene]- 8,8'-dicarboxaldehyde; 2,2'-bis[1,6,7-trihydroxy-3-methyl-5- isopropyl-8- aldehydonaphthalene]; 2,2'-bis[8-formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene]|
|Application Notes||Gossypol is potentially used as a male contraceptive by apparently inhibiting LH. The antiviral activity appears at low concentrations (up to 1 ug/mL) with a broad activity spectrum: RNA and DNA viruses, microviruses and herpes viruses.|
|Base Catalog Number||19521080|
|Biochemical Physiological Actions||Gossypol is a male antifertility agent and PAF antagonist/inhibitor. Gossypol is a poisonous pigment found in cottonseed and its name is derived from the botanical name of the cotton plant, Gossypium. Gossypium is extracted from selected hybrid species between two Gossypium species, Gossypium hirsutum and Gossypium barbadens. As a PAF antagonist/inhibitor, Gossypium markedly inhibited the contractile responses of guinea pig lung parenchyma strips stimulated with leukotriene B4, seukotriene D4, and PAF-acether.|
|Pack Size||100 mg|
|Personal Protective Equipment||Eyeshields, full-face particle respirator, Gloves, respirator cartridge, respirator filter|
|Solubility||Soluble in ethanol (25 mg/mL) and DMF (25 mg/mL); soluble in acetone and methanol (5 mg/mL), ether, chloroform.Very slightly soluble in petroleum ether. Freely soluble (with slow decomposition) in dilute aqueous solutions of ammonia and sodium carbonate.|
|UV Visible Absorbance||λmax: 358 nm (cyclohexane)(Lit.)|