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Fragile X Chemi probe
The Fragile X Syndrome is identified by an ampiflication of the FMR1 (CGG)n repeat region. The Fragile X CHEMITM probe is a digoxigenin labeled DNA probe (pFxa1NHE) which can be used in conjunction with the Sure Blot® CHEMITM Kit (Cat. No. 11S4250KIT) to detect (CGG) repeats in the FMR-1 gene. The same results are obtained as when using the standard P32-labeled probes, but without radioactivity. The amplification of the FMR-1 gene is detected on Southern blots by an increase in the band sizes. Also provided is a ready-to-use mixture of unlabeled and digoxigenin-labeled Lambda DNA/Hind III Molecular Weight Markers for convenient visualization on both ethidium bromide-stained agarose gels and Southern blots.
Fragile X CHEMI™ DNA Probe is used to detect Fragile X Syndrome, which is identified by an amplification of the FMR1 (CGG)n repeat region.
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Detection of Fragile X Syndrome
|Alternate Names||Digioxigenin labeled probe|
|Application Notes||Fragile X CHEMI™ DNA Probe is used to detect Fragile X Syndrome, which is identified by an amplification of the FMR1 (CGG)n repeat region.|
|Base Catalog Number||S1120DIG|
|Pack Size||10 Tests|
|Personal Protective Equipment||Personal-protective-equipment: If working with biological, toxic, hazardous or infectious samples; Hand protection: Latex, Nitrile or other plastic material gloves. Skin and body protection: Labcoat and sleves. Eye protection: Safety glasses with side-shields Hygiene measures: Handle in accordance with good industrial hygiene and safety practice. Use in Fume Hood|