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Ebselen, 20 mg

Ebselen, 20 mg

Synonyms 2-Phenyl-1,2-benzisoselenazol-3(2H)-one

CAS Number: 60940-34-3 Molecular Formula: C13N9NOSe Molecular Weight: 274.2

MDL Number: MFCD00210937

Packaging size: 20 mg

SKU 0215880920
$124.85
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Description

Product Description

Ebselen is a novel selenium-containing anti-flammatory agent.

Application Notes

Ebselen inhibits 5-LO, CO, NADPH oxidase, and protein kinase C. It is a potent antioxidant. It possesses a unique glutathione peroxidase-like activity. It is also shown to be an inhibitor of free radical induced apoptosis and neuroprotective agent.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Potent antioxidant

Specifications
SKU 0215880920
Alternate Names 2-Phenyl-1,2-benzisoselenazol-3(2H)-one
Application Notes Ebselen inhibits 5-LO, CO, NADPH oxidase, and protein kinase C. It is a potent antioxidant. It possesses a unique glutathione peroxidase-like activity. It is also shown to be an inhibitor of free radical induced apoptosis and neuroprotective agent.
Base Catalog Number 15880920
Biochemical Physiological Actions Ebselen inhibits mammalian lipoxygenases in the absence of thiol groups, and glutathione S-transferase and papain via the interaction with cysteine residues. Also inhibits indoleamine 2,3-dioxygenase by covalently modifying a cysteine residue, the effect being reversible with dithiothreitol. Inhibits oxidation of low density lipoproteins (LDL).
CAS # 60940-34-3
Hazard Statements H301-H331-H373-H410
Melting Point 180 - 181 °C (Lit.)
Molecular Formula C13N9NOSe
Molecular Weight 274.2
Pack Size 20 mg
RTECS Number DE4140750
Safety Symbol GHS06, GHS08, GHS09
Solubility Soluble in DMSO (25 mg/mL) and ethanol (10 mg/mL). Also soluble in chloroform (19.60 - 20.40 mg/mL - clear yellow solution).
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.