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Supplementation of cell culture media with glucosamine hydrochloride may enhance N-glycosylation of secreted proteins and affect differentiation of cell lines such as chondocytes and stem cells.
|Alternate Names||2-Amino-2-deoxy-D-glucose hydrochloride; Chitosamine hydrochloride|
|Application Notes||Supplementation of cell culture media with glucosamine hydrochloride may enhance N-glycosylation of secreted proteins and affect differentiation of cell lines such as chondocytes and stem cells.|
|Base Catalog Number||101782|
|Beilstein Registry Number||4157370|
|Biochemical Physiological Actions||Glucosamine, an amino sugar, is the precursor of the hexosamine biosynthetic pathway leading to the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is then used for making glycosaminoglycans, proteoglycans, and glycolipids.|
|Molecular Weight||215.63 g/mol|
|Optical Rotation||≤0.5 ppmIron ≤20 ppm|
|Particle Size||+72° ± 10° (c=1, water)|
|Source||Soluble in water (100 mg/mL).|
|Typical Working Concentration||Yes|