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Carboplatin, 100 mg

Carboplatin, 100 mg

$162.10

SKU: 0219887380

Synonyms
cis -Diammine[1,1-cyclobutane-dicarboxylato] platinum; (SP-4-2)-diammine[1,1-cyclobutanedicarboxylato (2-)-O,O']platinum
CAS Number:
41575-94-4
Molecular Formula:
C6H12N2O4Pt
Molecular Weight:
371.25
EC Number:
255-446-0
MDL Number:
MFCD00070464
Packaging size:
100 mg
Product Description

Carboplatin is a platinum coordination compound and antineoplastic agent that is related to cisplatin.

Application Notes

A study of γ-glutamyltransferase overexpression in carboplatin-treated HeLa cells, with relation to cell defense mechanisms, has been reported. Mouse peritoneal macrophages treated with carboplatin have been shown to produce enhanced IL-1α and TNF-α levels in tissue culture supernatants. A 96 well assay study of the action of carboplatin on 10 human ovarian cancer cell lines has been described.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antineoplastic agent

Specifications
SKU 0219887380
Alternate Names cis -Diammine[1,1-cyclobutane-dicarboxylato] platinum; (SP-4-2)-diammine[1,1-cyclobutanedicarboxylato (2-)-O,O']platinum
Application Notes A study of γ-glutamyltransferase overexpression in carboplatin-treated HeLa cells, with relation to cell defense mechanisms, has been reported. Mouse peritoneal macrophages treated with carboplatin have been shown to produce enhanced IL-1α and TNF-α levels in tissue culture supernatants. A 96 well assay study of the action of carboplatin on 10 human ovarian cancer cell lines has been described.
Base Catalog Number 19887380
Biochemical Physiological Actions Carboplatin is a platinum-based antineoplastic drug that damages DNA by forming intrastrand cross-links with neighboring guanine residues. Tumors acquire resistance to these drugs through the loss of DNA-mismatch repair (MMR) activity and the resultant decrease in the induction of programmed cell death.
CAS # 41575-94-4
EC Number 255-446-0
Hazard Statements H302 + H312 + H332-H317-H334-H360
Molecular Formula C6H12N2O4Pt
Molecular Weight 371.25
Pack Size 100 mg
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator cartridge, respirator filter
RTECS Number TP2300000
Safety Symbol GHS07, GHS08
Solubility Very slightly soluble in acetone and alcohol; sparingly soluble in water (10mg/mL-clear, colorless solution).
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure 0.0187 Pa at melting point (Lit.)
Documents

Datasheet

Datasheet