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Oxytetracycline, 100 g

Oxytetracycline, 100 g

$365.30

SKU: 0215179480

Synonyms
5-Hydroxytetracycline Dihydrate
CAS Number:
6153-64-6
Molecular Formula:
C22H24N2O9 • 2H2O
Molecular Weight:
496.46
EC Number:
201-212-8
MDL Number:
MFCD00151234
Packaging size:
100 g
Product Description

Oxytetracycline is a tetracycline analog.

Application Notes

Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). It is used for fluorescence measurements of hepatocytes.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic | Used for fluorescence measurements of hepatocytes

Specifications
SKU 0215179480
Alternate Names 5-Hydroxytetracycline Dihydrate
Application Notes Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). It is used for fluorescence measurements of hepatocytes.
Base Catalog Number 15179480
Biochemical Physiological Actions Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. Mode of Resistance: Active efflux, ribosome protection, tetracycline inactivation. Oxytetracycline inhibits translation, which results in cell death. It binds to the 30S ribosomal subunit and prevents the amino-acyl Trna from binding to the A site of the ribosome. The binding is reversible in nature. Oxytetracycline is lipophilic so it can easily pass through a cell membrane and passively diffuses through channels in the bacterial membrane.
CAS # 6153-64-6
EC Number 201-212-8
Melting Point 178.8-182.2 °C(Lit.)
Molecular Formula C22H24N2O9 • 2H2O
Molecular Weight 496.46
Optical Rotation -196.6° (0.1 N HCl), -2.1 (0.1 N NaOH), +26.5 (methanol) at 25 °C(Lit.)
Pack Size 100 g
Personal Protective Equipment Eyeshields, Gloves, respirator filter
pH 4.5 - 7.0(10% aq soln)
Solubility Soluble in water or 1N Hydrochloric acid.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.