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Chloramphenicol (γ-Irradiated), 20 mg

Chloramphenicol (γ-Irradiated), 20 mg

$26.25

SKU: 0219478720

Synonyms
D-(−)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide; D-(−)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol; D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]acetamide; Chloromycetin
CAS Number:
56-75-7
Molecular Formula:
C11H12Cl2N2O5
Molecular Weight:
323.13
Beilstein Registry Number:
2225532
EC Number:
200-287-4
MDL Number:
MFCD00078159
Packaging size:
20 mg
Specifications
SKU 0219478720
Alternate Names D-(−)-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-β-(4-nitrophenyl)ethyl]acetamide; D-(−)-threo-2-Dichloroacetamido-1-(4-nitrophenyl)-1,3-propanediol; D-threo-2,2-Dichloro-N-[β-hydroxy-α-(hydroxymethyl)-4-nitrophenethyl]acetamide; Chloromycetin
Application Notes Chloramphenicol is an inhibitor of translation on the 50S subunit at the peptidyltransferase step. Bacteriostatic (gram-negative bacteria). It is used as a seletion agent for transformed cells containing chloramphenicol resistance genes. This product has also been shown to inhibit the inactivation of pentobarbital, codeine, dilantin, analgesic-antipyretic drugs and oral anticoagulants in veterinary studies.
Base Catalog Number 19478720
Beilstein Registry Number 2225532
Biochemical Physiological Actions Mode of Action: Inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step (elongation inhibition). Bacteriostatic. Mode of Resistance: Acetylation by chloramphenicol acetyltransferase (cat gene).
CAS # 56-75-7
Density 1.586 g/mL (Lit.)
EC Number 200-287-4
Extinction Coefficient E1% = 298 (278 nm)(Lit.)
Grade &gamma, -Irradiated
Hazard Statements H350
Melting Point 149 - 155 °C
Molecular Formula C11H12Cl2N2O5
Molecular Weight 323.13
Optical Rotation (c=5 ethanol) +18° ± 5°
Pack Size 20 mg
Personal Protective Equipment Eyeshields, full-face particle respirator, Gloves, respirator filter, respirator cartridges
pKa approximately 5.5(Lit.)
RTECS Number AB6825000
Safety Symbol GHS08
Solubility Soluble in methanol (50 mg/mL - clear, pale yellow solution), butanol, ethyl acetate, acetone, ethanol, propylene glycol; slightly soluble in water, ether; insoluble in benzene, petroleum ether, vegetable oils.
Typical Working Concentration 5 -20 ug/mL(Lit.)
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance λmax: 278 nm (Lit.)
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Datasheet

Datasheet