Happy Thanksgiving! Get a $50 Giftcard on us when you spend $400 or more, use promo code at the checkout: THANKYOU50. Offer ends Nov. 30th, 2020.
Potent in the inhibition of protein phosphatases 1 and 2A (PP1 and PP2A)
Similar to Microcystin-LR, but with increased water solubility
Useful for affinity purification of PP2A
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
|Alternate Names||1,4,8,11,15-Pentaazacyclononadecane, cyclic peptide|
|Application Notes||Useful for affinity purification of PP2A|
|Base Catalog Number||15838090|
|Biochemical Physiological Actions||Non-cell permeable protein phosphatase inhibitor. Hepatotoxic, cyclic peptide related to microcystin LR with a similar activity profile. It does not induce any effects on mouse skin or human fibroblasts.Potent inhibitor of protein phosphatases types 1 and 2A. Tumor promoter in experimental animal model; at higher doses, causes massive liver hemorrhage. Tumor-promoting effect is due to increasing oxidative stress, as evidenced by reduced levels of glutathione and appearance of oxidative damage in DNA bases.|
|Hazard Statements||H300 +H310 + H330-H315-H317-H319-H335|
|Pack Size||500 UG|
|Solubility||Soluble in DMSO and methanol (2 mg/mL), water (15% methanol v/v), ethanol.|
|Usage Statement||Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.|