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Nodularin, 500 UG

Nodularin, 500 UG

$681.20

SKU: 0215838090

Synonyms
1,4,8,11,15-Pentaazacyclononadecane, cyclic peptide
CAS Number:
118399-22-7
Molecular Formula:
C41H60N8O10
Molecular Weight:
825
MDL Number:
MFCD16659855
Packaging size:
500 UG
Product Description

Potent in the inhibition of protein phosphatases 1 and 2A (PP1 and PP2A)
Similar to Microcystin-LR, but with increased water solubility

Application Notes

Useful for affinity purification of PP2A

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Specifications
SKU 0215838090
Alternate Names 1,4,8,11,15-Pentaazacyclononadecane, cyclic peptide
Application Notes Useful for affinity purification of PP2A
Base Catalog Number 15838090
Biochemical Physiological Actions Non-cell permeable protein phosphatase inhibitor. Hepatotoxic, cyclic peptide related to microcystin LR with a similar activity profile. It does not induce any effects on mouse skin or human fibroblasts.Potent inhibitor of protein phosphatases types 1 and 2A. Tumor promoter in experimental animal model; at higher doses, causes massive liver hemorrhage. Tumor-promoting effect is due to increasing oxidative stress, as evidenced by reduced levels of glutathione and appearance of oxidative damage in DNA bases.
CAS # 118399-22-7
Hazard Statements H300 +H310 + H330-H315-H317-H319-H335
Molecular Formula C41H60N8O10
Molecular Weight 825
Pack Size 500 UG
RTECS Number GU2294250
Safety Symbol GHS06
Solubility Soluble in DMSO and methanol (2 mg/mL), water (15% methanol v/v), ethanol.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Citations