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Ethylenediamine, tetraacetic acid

Ethylenediamine, tetraacetic acid

$95.20

Key features and details

Ethylenediamine Tetraacetic Acid

SKU: 04800682-CF

Synonyms
EDTA; (Ethylenedinitrilo)tetraacetic acid; Edathamil; Ethylenedinitrilotetraacetic acid
CAS Number:
10378-22-0
Molecular Formula:
C10H16N2O8
Molecular Weight:
376.204 g/mol
Beilstein Registry Number:
1716295
EC Number:
200-449-4
MDL Number:
MFCD00003541
Product Description

Ethylenediamine Tetraacetic Acid

Application Notes

Ethylenediamine tetraacetic acid (EDTA) is a calcium chelator used to eliminate inhibition of enzyme catalyzed reactions due to traces of heavy metals. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. EDTA prevents platelet aggregation and is therefore the preferred anticoagulant for platelet counts. It is an inhibitor of metalloproteases and metal-activated proteases. It acts as a chelator of the zinc ion in the active site of metalloproteases, but EDTA can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. EDTA interferes with biological processes which are metal-dependent. It is a buffer component.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Chelating agent | Buffer Component

Specifications
SKU 04800682-CF
Alternate Names EDTA; (Ethylenedinitrilo)tetraacetic acid; Edathamil; Ethylenedinitrilotetraacetic acid
Application Notes Ethylenediamine tetraacetic acid (EDTA) is a calcium chelator used to eliminate inhibition of enzyme catalyzed reactions due to traces of heavy metals. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. EDTA prevents platelet aggregation and is therefore the preferred anticoagulant for platelet counts. It is an inhibitor of metalloproteases and metal-activated proteases. It acts as a chelator of the zinc ion in the active site of metalloproteases, but EDTA can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. EDTA interferes with biological processes which are metal-dependent. It is a buffer component.
Base Catalog Number 800682
Beilstein Registry Number 1716295
CAS # 10378-22-0
EC Number 200-449-4
Format Powder
Grade Electrophoresis grade
Hazard Statements H319
Melting Point 245 deg C
Molecular Formula C10H16N2O8
Molecular Weight 376.204 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Gloves
pKa 2.0, 2.7, 6.2, 10.3 (Lit.)
Purity >99.5%
RTECS Number AH4025000
Safety Symbol GHS07
Solubility SOL IN SOLN OF ALKALI HYDROXIDES
Typical Working Concentration EDTA is an inhibitor of metalloproteases and metal-activated proteases at an effective concentration of 1-10 µM.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure 1.50X10-12 mm Hg at 25 deg C /Extrapolated/