Dexamethasone, Water Soluble

Xanthine Oxidase

Application Notes

Xanthine oxidase can be used to generate superoxide radicals for use in the enzymatic assay of superoxide dismutase. The addition of xanthine oxidase as a superoxide donor to hepatic stellate cells (HSC) cell cultures strongly increased procollagen I synthesis.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Superoxide radical donor

SKU	02199518-CF
Alternate Names	Xanthine: oxygen oxidoreductase; XOD; EC 1.17.3.2
Application Notes	Xanthine oxidase can be used to generate superoxide radicals for use in the enzymatic assay of superoxide dismutase. The addition of xanthine oxidase as a superoxide donor to hepatic stellate cells (HSC) cell cultures strongly increased procollagen I synthesis.
Base Catalog Number	199518
Biochemical Physiological Actions	Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids. It plays a vital role in the metabolism of some drugs, as well as purines and pyrimidines. It is also known to be a biological source of reactive oxygen species.
CAS #	9002-17-9
EC Number	232-657-6
Extinction Coefficient	E1% = 11.7(Lit.)
Format	Powder
Personal Protective Equipment	Eyeshields, Gloves, Respirator filter
RTECS Number	RQ8455000
Source	Buttermilk
Specific Activity	Activity: 1 - 4 u/mg protein
Unit Definition	The amount of enzyme which catalyzes the oxidation of one micromole of xanthine to uric acid per minute at 25 °C and pH 7.5.
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.