Ciprofloxacin is most commonly used to treat infections of the skin, bone, sinus, lung, abdomen, and bladder. It can also be used to treat some sexually transmitted infections. Additionally, ciprofloxacin can be used after exposure to inhalation anthrax to reduce the chance of developing an infection.
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Fluorinated quinolone antibacterial agent
|Alternate Names||Cipro; Ciproxan; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperzinyl)-3-quinolinecarboxylic acid HCl H2O|
|Application Notes||Ciprofloxacin is most commonly used to treat infections of the skin, bone, sinus, lung, abdomen, and bladder. It can also be used to treat some sexually transmitted infections. Additionally, ciprofloxacin can be used after exposure to inhalation anthrax to reduce the chance of developing an infection.|
|Base Catalog Number||199020|
|Biochemical Physiological Actions||During the proliferation phase of a bacterium a segmental twisting and untwisting of the chromosomes take place. An enzyme called DNA gyrase plays a decisive part in this process. Ciprofloxacin inhibits this DNA gyrase in a way that arrests the bacterial metabolism, since vital information can no longer be read from the bacterial chromosome. Ultimetaly it affect DNA replication & Cell division.|
|Melting Point||225-257 deg C, decomposes|
|Molecular Weight||385.82 g/mol|
|pH||pH range for the 1.0% aqueous concentrates in vials is 3.3 to 3.9; the pH range for the 0.2% ready-for-use infusion solutions is 3.5 to 4.6|
|Solubility||Soluble in dilute (0.1N) <a class="pubchem-internal-link CID-313" href="https://pubchem.ncbi.nlm.nih.gov/compound/hydrochloric%20acid">hydrochloric acid</a>; practically insoluble in <a class="pubchem-internal-link CID-702" href="https://pubchem.ncbi.nlm.nih.gov/compound/ethanol">ethanol</a>|
|Typical Working Concentration||Effective Working Concentration: 5-25 ug/mL (average is 10 ug/mL). Ciprofloxacin hydrochloride is typically used for approximately 12 to 20 days in cell culture media with the media being changed every 3 to 4 days.|
|Vapor Pressure||2.85X10-13 mm Hg at 25 deg C (est)|